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of autoantigen-specific Tregs and Teffs in humans, the selection of optimal TCR to produce protective Tregs, innovative humanized T1D pre-clinical models to test their efficacy and safety, the development
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are particularly important. Microglia act as drivers of pathogenesis, yet also have crucial beneficial activities in these diseases, controlling the resolution of inflammation and CNS regeneration. The goal
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neurophysiological methods including electroencephalography (EEG) and event-related potentials. However, healthcare professionals often face a dilemma between the accuracy of these diagnostic tools and their immediate
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