PhD position: Janus nanorods by supramolecular self-assembly of polymers in solution for biological applications
27 Mar 2024
Job Information
- Organisation/Company
Institut des Molécules et Matériaux du Mans- Department
Chemistry- Research Field
Chemistry » Physical chemistry- Researcher Profile
First Stage Researcher (R1)- Country
France- Application Deadline
31 May 2024 - 12:00 (Europe/Paris)- Type of Contract
Temporary- Job Status
Full-time- Offer Starting Date
1 Oct 2024- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
We have very recently proposed an original strategy to prepare Janus nanorods (JNR) by supramolecular self-assembly in solution of two different polymers bearing complementary hydrogen bonding units. The hydrogen bonding units have been designed not only to drive the self-assembly into one-dimensional structures (nanorods), but also to force each polymer on either-side of the rods (Janus character) independently of the chemical structure of the polymer arms.
Although this strategy has been proven successful, its full potential is far from being explored and many questions remain. For that reason, the objective of this PhD will be to:
- Explore the role of the preparation process on the characteristics of new biocompatible JNR (length, diameter, dispersity) and determine the mechanism by which the JNR are formed in solution through hydrogen bonding.
- Investigate how changing the chemical structure, functionality and molar mass of the polymers affects their characteristics (length, diameter, dispersity, and functionality)
- Investigate the adhesion and responsiveness of JNR onto polysaccharide matrices since JNR will be used as double-sided nano-tapes for cell and organoid culture.
For that purpose, state-of-the art physico-chemical characterization techniques of polymers will be used including: light, X-ray and neutron scattering, Transmission Electron Microscopy (also in cryo-mode), UV-Vis, DOSY/NOESY NMR spectroscopy and QCM-D in particular. The PhD will also have the opportunity to visit the other partners’ laboratories to get some knowledge about the scientific expertise of the other partners.
Requirements
- Research Field
- Chemistry » Physical chemistry
- Education Level
- Master Degree or equivalent
Skills/Qualifications
Polymer scientist and/or physical chemist having an interest in the characterization of polymer supramolecular self-assemblies in solution.
Experience in light, X-ray or neutron scattering, Transmission Electron Microscopy, or supramolecular self-assembly would be an asset.
- Languages
- ENGLISH
- Level
- Excellent
Additional Information
Additional comments
Acquired financial support: French National Research Agency ANR-PRC 2023-2027
Salary: 1400-1600 euros / month
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Institut des Molécules et Matériaux du Mans
- Country
- France
- Geofield
Where to apply
[email protected]
Contact
- City
Le Mans- Website
http://immm.univ-lemans.fr- Street
Avenue Olivier Messiaen- Postal Code
72085
STATUS: EXPIRED