PhD scholarship in P450-based Biocatalytic Processes for the Pharmaceutical Industry – DTU Chemical Engineering

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PhD scholarship in P450-based Biocatalytic Processes for the Pharmaceutical Industry – DTU Chemical Engineering
Kgs. Lyngby, Denmark
Job Description

The PROSYS Centre at DTU Chemical Engineering is looking for a PhD candidate. 
This project is part of a new collaboration with the University of Queensland (Australia) and the pharmaceutical company, Astra Zeneca (Gothenburg, Sweden). All three groups (DTU, UQ and AZ) have excellent and long-standing expertise in biocatalysis in general, and P450 cytochromes-based chemistry in particular. These enzymes are of particular interest in the pharmaceutical industry, but scale-up remains challenging. This PhD project will have a focus on process scale-up and use the latest enzymes available from the lab in Australia, to design and build a suitable reactor, as well as analyze kinetics and stability of such systems. The collaboration will extend to planned visits to Australia and Sweden as part of the work. The majority of the work will be experimental, but modelling approaches will also be used to complement the experimental work. 
The biocatalysis team at DTU Chemical Engineering consists of around 15 scientists and engineers. Expertise is available on kinetics and stability measurements. The team have access to labs equipped with alternative reactors and excellent analytical equipment. 
Responsibilities and qualifications
The position includes the following tasks:

• Running biocatalytic reactors, assessed with suitable analytical techniques
• Kinetic evaluation of alternative enzyme systems
• Stability evaluation of alternative enzyme systems

Our expectations of you:

• You must have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree.
• A master’s degree in chemical or biochemical engineering or biotechnology or a related discipline is required.

Approval and Enrolment 
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU's rules for the PhD education . 
Assessment
The assessment of the applicants will be made by Professor John Woodley. 
We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.
Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years.
You can read more about career paths at DTU here .
Further information 
Further information may be obtained from Professor John Woodley, e-mail: [email protected] . 
You can read more about DTU Chemical Engineering at www.kt.dtu.dk .
If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark . Furthermore, you have the option of joining our monthly free seminar “PhD relocation to Denmark and startup “Zoom” seminar ” for all questions regarding the practical matters of moving to Denmark and working as a PhD at DTU. 
Application procedure 
Your complete online application must be submitted no later than 27 February 2024 (23:59 Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply now", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

• A letter motivating the application (cover letter)
• Curriculum vitae 
• Grade transcripts and BSc/MSc diploma (in English) including official description of grading scale.

You may apply prior to ob­tai­ning your master's degree but cannot begin before having received it. 
Applications received after the deadline will not be considered.
All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.
The Department of Chemical and Biochemical Engineering is a leading Department focused among other many fields on the development of new pharmaceutical processes (modelling, experimental and incorporating scale-up). The Department has around 250 employees. There are excellent facilities available for experimental work in the laboratory, as well as pilot plant. The Department has excellent analytical facilities. 
Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

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Job Info

• Job Identification 3123
• Job Category Phd
• Posting Date 02/05/2024, 07:55 AM
• Apply Before 02/27/2024, 05:59 PM
• Locations Søltofts Plads, Kgs. Lyngby, 2800, DK

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