PhD Position in the MSCA-DN GlyCanDrug: Testing and validation of inhibitors by engineered cell-based glycan arrays

16 Feb 2024
Job Information

Organisation/Company

GlycoDisplay ApS

Research Field

Biological sciences » Biological engineering

Researcher Profile

First Stage Researcher (R1)

Country

Denmark

Application Deadline

29 Feb 2024 - 23:59 (Europe/Copenhagen)

Type of Contract

Temporary

Job Status

Full-time

Is the job funded through the EU Research Framework Programme?

HE / MSCA

Marie Curie Grant Agreement Number

101119601

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

GlyCanDrug is a glycoscience-oriented European Training Network funded in the framework of HORIZON Europe Marie Skłodowska-Curie Doctoral Networks (MSCA-DN). Within GlyCanDrug, Doctoral Candidates (DCs) will be equipped with a thorough multifaceted knowledge of the potential of glycoscience in the discovery of cancer precision therapeutics and the necessary transferable skills. GlyCanDrug will provide an international, intersectoral and interdisciplinary educational program, according with the EU Principles for Innovative Doctoral Training. This will put DCs in an advantageous position for job opportunities in both academia and industry.

DC10: We are seeking a highly motivated and intellectually curious PhD candidate to contribute to this project at GlycoDisplay ApS. GlycoDisplay is a spin-out of Copenhagen Center for Glycomics, University of Copenhagen, which is world leading within the field of glycoengineering and glycomics. This PhD project will focus on the design and engineer optimal cell models for screening and validation of inhibitors for the sialyltransferases (ST)s and fucosyltransferases (FT)s isoenzymes. The DC will be trained in glycoengineering technologies using CRISPR/Cas9, cell-based glycan array screening method, as well as synthesis of glycomimetics and high-throughput screening of libraries of compounds through secondments.

PLANNED SECONDMENTS. (1) University of Florence, Italy,  synthesis of glycomimetics. (2) University of Ljubljana, Slovenia, virtual screening to discover inhibitors for selected glycotransferases.

PhD School enrolment: Graduate Program for Cellular & Genetic Medicine (CeGem), University of Copenhagen

Requirements

Research Field

Biological sciences » Biological engineering

Education Level

Master Degree or equivalent

Skills/Qualifications

- Master degree in biology, molecular biology, or related fields.

- Good level of English proficiency (understood, spoken and written).

- ability to work in a team as well as work independently

Languages

ENGLISH

Level

Excellent

Research Field

Biological sciences » Biological engineering

Internal Application form(s) needed
GlyCanDrug_General call for applications&Application form_Euraxess_0.pdf
English
(450.33 KB - PDF)
Download
GlyCanDrug_Call for DC10.pdf
English
(493.75 KB - PDF)
Download
Additional Information
Benefits

The salary of the DCs will be paid according to the MSCA rules. See: https://marie-sklodowska-curie-actions.ec.europa.eu/calls/msca-doctoral-networks-2022

Eligibility criteria

The position is open to candidates (of any nationality) that fulfil the requirements set for the DCs funded by MSCA. Equal opportunities policy without distinction on the grounds of gender, racial or ethnic origin, religion or belief, disability, age or sexual orientation will be applied. Eligibility criteria for MSCA-DN researchers https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/…  pages 80-82/111
At the time of recruitment applicants must fulfil the following rules:
➢ Experience: eligible applicants must not have a PhD yet, whereas they must have a Master degree.
➢ Mobility: the DCs must not have resided in the country where the research training activities will take place for more than 12 months in the 3 years prior to the recruitment date (and not have carried out their main activity (work, studies) in that country).

Selection process

APPLICATION PROCEDURE
Applicants can apply for up to 3 projects within the consortium, indicating the order of preference. All applications will be checked for eligibility. Incomplete applications will be ignored. Applications must be in English. The applicant must send the following documents (IN A ONE SINGLE PDF FILE) to the email specified (e-mail: [email protected] ) within application deadline. 
1) an updated CV (EU pass format: https://europa.eu/europass/it/create-europass-cv  including the details of education/qualifications, work experience, language skills and other relevant skills);
2) a motivation letter (max 1 page);
3) full names, affiliation and email addresses of at least 2 potential referees (at least one of them from one former supervisor and/or lecturer);
4) the scan of the degree (usually the Master Degree) which would formally entitle him/her to embark on a doctorate, either in the country in which the degree was obtained or in the country in which the researcher will be recruited. In case the degree has not been obtained yet, it is necessary to send an official declaration of the university stating that the degree will be obtained before the expected starting date and the documents reported at point 5);
5) a certified document indicating the ranking and marks at the Master Degree as well as the courses/modules they have attended. This document is mandatory for applicants who do not have yet obtained the degree at the time of the application.
6) a summary of the Master Degree thesis or a brief description of the past scientific activity.
7) format application. Before the signing of the GA, the format application will be sent to people interested upon request on the email: [email protected]
8) Copy of a valid ID/Passport.

ASSESSMENT CRITERIA
Supervisors will pre-select candidates for each position, based on the information included in the application procedure that will be evaluated against the following criteria:
- Educational record;
- scientific quality of the applicant’s CV;
- expected individual impact and benefit to the fellow and to the project;
- previous experience in the subject of the GlyCanDrug research programme.
Shortlisted candidates will be invited for interviews with multiple supervisors from the network (online or in-person). Good level of English proficiency (understood, spoken and written) will be considered. Candidates will be notified of the outcome.

Additional comments

Start of employment is foreseen between January-November 2024. The starting date of each PhD contract shall be set according to local rules of the Beneficiary institution and in agreement with the local supervisor of the selected DC project. 

The position is open to candidates of any nationality, as long as they fulfil the requirements set for the DCs funded by MSCA (Annex A).The applicant must send the documents in the Annex A to the email specified ([email protected] ) within application deadline, clearly indicating in the subject “Application for DC1 position”.

Work Location(s)

Number of offers available

1

Company/Institute

GlycoDisplay ApS

Country

Denmark

City

Copenhagen

Postal Code

2200

Street

Blegdamsvej 3B

Where to apply

E-mail

[email protected]

Contact

City

Copenhagen N

Website

http://glycodisplay.com/

Street

Blegdamsvej 3B

Postal Code

2200

E-Mail

[email protected]

STATUS: EXPIRED