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triazine-containing analogues of phenylalanine (Chem. Eur. J (2015) 21 14376) to generate new probe molecules for chemical proteomics and chemical biology. Dependent upon the particular target these might
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proteomics, the quantitative study of the molecules that are the building blocks of life. Reproducibility in ‘omics work is crucial to allow for validation of biomarkers and pathways associated with different
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: An examination of sex-specific changes in the metabolome and proteome of the prefrontal cortex in alcoholism and depression Psychiatric disorders such as anxiety and depression are often present in patients with
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of Resveratrol and similar compounds on lifespan and ageing (senescence) markers in Killifish using RNA-seq and proteomic approaches. Once novel pathways are identified, the project will then use gene editing
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Conway Institute of Biomolecular & Biomedical Research | Dublin Bar, Leinster | Ireland | 19 days ago
microscopy, proteomics, genomics, etc.) will be utilised. The produced three-dimensional in vitro disease models will be characterised using an array of biophysical, biochemical and biological methods. Various
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the powerful companion technology of chemical proteomics, we now envision the prospect of mapping biological coverage systematically in a native cellular context. In this project, we will develop
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project will provide high-quality, specialised training in cutting edge omics (proteomics, lipidomics, transcriptomics), modern molecular biology techniques as well as training in various infection models
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will provide high-quality, specialised training in cutting edge omics (proteomics, lipidomics, transcriptomics), modern molecular biology techniques as well as cultivation of model organisms
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-of-the-art techniques in cell biology, genetics, molecular biology and proteomic, this project aims at characterizing a novel signalling pathway modulating root nodule symbiosis. The insights gained from
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pattern recognition receptor-cytokine responses to oral pathogens, leading to adopting a proteomic approach in the identification of therapeutic targets for resolution of chronic inflammatory mucosal