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PhD Scholarship for a chemistry, materials or chemical engineering student looking to apply their skills in electrode development for electrocatalytic CO2 reduction. Research will be conducted within the Applied Chemistry and Environmental Science discipline in the School of Science. PhD...
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This project will examine the behaviour of nanocarriers at cell/bacteria surfaces and response to biological environments and molecules (such as proteins). Research will utilize a suite of cutting
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anti-cancer roles of these compounds via modulation of the immune system, with particular focus on effector (Teff) and regulatory (Treg) T cell populations. This project aims to identify changes in
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PhD Scholarship in ‘Using nanoparticles to enhance the immune response and improve vaccine efficacy’
to the vaccine, particularly regarding inducing a T cell response. Our lab focuses on viral sized nanoparticles as adjuvanting vaccine delivery systems to improve both the antibody mediated and cellular immune
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role in determining cell function and identity. These marks are actively modulated by different conditions including stress, lifestyle, sex and age or vaccination [2-3]. This project will systematically
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characterisation techniques: surface and spectroscopic analysis, electrochemical study, mineralogy analysis, and synchrotron technology. Environmental contamination with uranium has posed a significant problem owing
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RNAseq, epigenetics, multicolour flowcytometry (up to 27 simultaneous markers on cells), cell sorting, multiplex cytokine analysis (Luminex) as well as classical immunological techniques, e.g. ELISA
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cells or Tregs) and immune-cell mediated inflammation. Using the immune system clear the tumours provides potentially more effective approaches than current treatments. Moreover, it may be possible to use
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, M.; Ang, C.-S.; Mitchell, A.; Zhong, Q.-Z.; Zheng, T.; Kent, S. J.*; Caruso, F.* Protein Precoating Modulates Biomolecular Coronas and Nanocapsule–Immune Cell Interactions in Human Blood. J. Mater
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.; Kent, S. J.; Caruso, F. Influence of Poly(Ethylene Glycol) Molecular Architecture on Particle Assembly and Ex Vivo Particle–Immune Cell Interactions in Human Blood. ACS Nano 2021, 10.1021/acsnano.1c01642