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, such as mitochondria-endoplasmic reticulum contacts, mitochondrial fission, movement and transfer, and their role for neuron-glia communication. We use both in vitro and ex vivo systems with advanced
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purification from human brain tissue, blood samples and cerebrospinal fluid as well as from mouse models and neuronal cultures. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) will be used to identify
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on single-cell RNA sequencing to study pain-sensing neurons plasticity in health and disease. Duties You will combine pain behavioural assessments, histology, dissection, cell culture, intrathecal injection
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laboratory is aimed at elucidating mechanisms of neuronal vulnerability and resistance with the goal of identifying new molecular targets for the treatment of neurodegenerative diseases, with emphasis
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conditions and in various disease states. Research projects include a broad range of studies on the molecular and cellular levels, networks of neurons, and the organization of the nervous system as a whole