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Instituto de Investigação e Inovação em Saúde da Universidade do Porto (i3S) | Portugal | 22 days ago
developed; c. Experience in primary neuronal cultures carried out in the context of microfluidics; d. Experience in intracellular trafficking studies; e. Experience in confocal microscopy and the use of image
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Validation of novel molecular targets from anti-inflammatory and cytoprotective molecules in neurons
targets through the investigation of anti-inflammatory peptides derived from animal venoms. The activities involve elucidating the peptide effects in cell culture, and in vivo using inflammatory and pain
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Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt | Leipzig, Sachsen | Germany | 13 days ago
the anatomical distribution, molecular signature and neurocircuitry architecture of these neurons. Furthermore, we want to investigate the longitudinal effects governed by these neurons to determine their
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(sECM) to generate in-vivo-like cell diversity. isolate tooth-specific endothelial cells and use them to create perfusable blood vessels derive human trigeminal neurons from hESCs and culture them in a 3D
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blood vessels derive human trigeminal neurons from hESCs and culture them in a 3D matrix. combine all these elements in an integrated free-floating 3D bioengineered tooth emulation system, further
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targets through the investigation of anti-inflammatory peptides derived from animal venoms. The activities involve elucidating the peptide effects in cell culture, and in vivo using inflammatory and pain
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of vast numbers of neurons gives rise to the plethora of animal behaviors. The interdisciplinary research spans from imaging neural circuits at the nanoscale to analyzing neural activity in a freely moving
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interactions between glioma and neuronal cells. Job description The student will develop physiologically relevant cell culture models to recapitulate the glioma microenvironment in vitro. The functional
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context (neuronal and non-neuronal) and develop stable biosensor cell lines. Biosensor cells will be challenged with different stimuli to identify conditions that favor or impair the pathological
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investigate the intricate bidirectional interactions between glioma and neuronal cells. Job description The student will develop physiologically relevant cell culture models to recapitulate the glioma