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Janet Deane at the Cambridge Institute for Medical Research. Our lab uses a wide range of techniques to study how altered lipid metabolism drives changes in the cellular proteome causing neuronal
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Janet Deane at the Cambridge Institute for Medical Research. Our lab uses a wide range of techniques to study how altered lipid metabolism drives changes in the cellular proteome causing neuronal
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possible environment for world-class fundamental and clinical research in neurodegeneration and mechanisms of mental health while they strive to promote a culture of collaboration, research integrity
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closely with Dr Alfredo Iacoangeli at the Department of Biostatistics and Health Informatics, and Professor Ammar Al-Chalabi in addition to collaborating with the members of King’s Motor Neurone Disease
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mechanisms that regulate the integrity of mitochondria and maintain normal neuronal function and survival. The group uses Drosophila and cellular models to elucidate the molecular mechanisms of pathogenesis
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algorithms to modulate synaptic interactions in neuronal network cultures. These tools will be embedded in closed-loop multielectrode array experiments and used to shed new light on how electrical rhythms
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Overview Our goal is to harness the therapeutic use of stem cells to repair neuronal damage in the brain. It is our hypothesis that neuroprotective factors that are naturally present in our body
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that you hold or be close to award of a doctorate (PhD/DPhil) in Neuroscience, have a proven track record in cell culture (particularly iPSC and ESC-derived neuronal cell culture) and experience in molecular
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conduct your own experimental work and provide expertise for the establishment and use of iPSC-derived neuronal cultures. Additionally, you will carry out collaborative projects with colleagues in
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aims of the current PhD project are: i) Design and establish base editing therapeutic technology at our centre; ii) Evaluate the in vitro efficacy of the therapeutic vector system in iPSC derived neurons