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Our lab is interested in elucidating molecular mechanisms that control transcriptional programs in neuronal cells with the aim of preventing/reversing neurodegeneration. Various projects
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endeavor aimed at addressing neurodegeneration, aging and brain resilience. Diseases and associated issues of cognitive decline like Alzheimer's, Parkinson's, dementia, and related ailments are increasing
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endeavor aimed at addressing neurodegeneration, aging and brain resilience. Diseases and associated issues of cognitive decline like Alzheimer's, Parkinson's, dementia, and related ailments are increasing
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pathogen Porphyromonas gingivalis (Pg) in neurodegeneration under the training and supervision of a staff lead. You will work closely with research staff in support of the laboratory research. Some of this
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for neurodegeneration. You will perform and support lab experiments working both independently and in a team to support a multidisciplinary collaboration for T cell engineering. Your work will focus primarily
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genetic screens in a range of medically relevant areas, such as cancer, neurodegeneration and infectious disease. The goal of this work is to understand (1) the biology of cancer development and identify
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engineering approaches to tackle challenging human health problems like protein misfolding diseases that cause neurodegeneration. One particular type of tool we exploit for these purposes are small, single
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tools, including ultracomplex CRISPR/Cas9 libraries, to conduct genetic screens in a range of medically relevant areas, such as cancer, neurodegeneration and infectious disease. The goal of this work is
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conditions. His research group also studies how these pathways go awry in human diseases such as cancer, neurodegeneration, and metabolic syndrome to engineer new therapeutic modalities. This position will
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reagents (e.g. nanobodies) to both study and modulate protein quality control pathways that regulate cellular protein folding and degradation in health and disease conditions (e.g. cancer, neurodegeneration