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, based on innovative separations coupled (HYPhEnated) to mass spectrometry to: (i) structurally characterize Ig, resolving the proteoforms complexity of multiply glycosylated immunoglobulins, and (ii
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pipelines to examine datasets of DNAseq, RNAseq, Ribosome profiling, CRISPR screens, and mass spectrometry. We expect the successful applicant to team up with other computational and experimental researchers
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two approaches to better understand through which mechanisms exposure to EDCs impacts health: You will integrate High-Resolution Mass Spectrometry (HRMS)- based measurements of EDCs, biological effects
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frontrunner in applying state-of-the-art mass spectrometry-based proteomics in the area of benign hematology. We are a vibrant, international group of 35-40 colleagues (consisting of group leaders, postdocs
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, and mass spectrometry. We expect the successful applicant to team up with other computational and experimental researchers in the lab and be involved in the writing of scientific papers, project reports
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blood cancer myeloproliferative neoplasms (MPN) (Jutzi and Marneth et al., 2022). This disease is driven by overactivation of thrombopoietin receptor MPL. Using mass spectrometry, you will generate a full
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, recombinant synthesis of proteins. Experience with, or a strong willingness to learn, computational chemistry techniques. Proficiency in analytical techniques like NMR, Mass Spectrometry, and Chromatography
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Detection Laboratory (TDLab) focuses on the detection of species in trace levels with a higher emphasis on the gas phase. For this, we use various analytical laboratory instruments based on mass spectrometry
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analytical laboratory instruments based on mass spectrometry and Fourier transform spectroscopy (FTS) and are developing new laser-based spectroscopic instruments for specific applications. These applications
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research, including mass spectrometry, NMR spectroscopy and structural biology/cryogenic electron microscopy. In addition, The Bijvoet Centre has a state-of-the-art Protein Research Centre that is equipped