Research Specialist, Crona Lab

University of North Carolina at Chapel Hill, United States

Updated: 26 days ago
Location: Chapel Hill, NORTH CAROLINA
Job Type: FullTime
Deadline: 29 May 2024

Posting Information
Posting Information


Department SOP-DPET-452200
Career Area Research Professionals
Is this an internal only recruitment? No
Posting Open Date 05/20/2024
Application Deadline 05/29/2024
Position Type Permanent Staff (SHRA)
Position Title Research Specialist - Contributing
Salary Grade Equivalent GN08
Working Title Research Specialist, Crona Lab
Position Number 20014181
Vacancy ID P019112
Full-time/Part-time Permanent/Time-Limited Full-Time Permanent
If time-limited, estimated duration of appointment
Hours per week 40
Work Schedule
M-F 8am – 5pm
Work Location Chapel Hill, NC
Position Location North Carolina, US
Hiring Range $54,172 - $66,210
Pay Band Information
To learn more about the pay band for this branch and role, please see the Career Banding rates spreadsheet .

Position Summary Information


Be a Tar Heel!
A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation’s top public universities . Known for its beautiful campus, world-class medical care, commitment to the arts and top athletic programs, Carolina is an ideal place to teach, work and learn.
One of the best college towns and best places to live in the United States, Chapel Hill has diverse social, cultural, recreation and professional opportunities that span the campus and community.
University employees can choose from a wide range of professional training opportunities for career growth, skill development and lifelong learning and enjoy exclusive perks for numerous retail, restaurant and performing arts discounts, savings on local child care centers and special rates on select campus events. UNC-Chapel Hill offers full-time employees a comprehensive benefits package , paid leave, and a variety of health, life and retirement plans and additional programs that support a healthy work/life balance.
Primary Purpose of Organizational Unit
The UNC Eshelman School of Pharmacy (www.pharmacy.unc.edu) is one of six health science schools (Pharmacy, Nursing, Dentistry, Social Work, Public Health, Medicine) at the University of North Carolina at Chapel Hill and is one of the oldest health science academic programs at Chapel Hill. The School teaches approximately 600 PharmD students and 145 graduate students. The School has built a reputation for its continued pursuit of excellence, rigorous education and training programs, cutting-edge multidisciplinary research, progressive pharmacy practices, efficient business operations, and its outstanding faculty, staff, and students. The School was named the number one School of Pharmacy in the U.S. by the U.S. News and World Report. The School has experienced unprecedented growth and success and continues to strategically position itself for sustained impact, as articulated in the School’s Strategic Plan (https://pharmacy.unc.edu/about/oe/strategic-plan/).
Our Vision is to be the global leader in pharmacy and pharmaceutical sciences. Our Mission is to prepare leaders and innovators to solve the world’s most pressing health care challenges. We are Advancing Medicine for Life through innovation and collaboration in pharmacy practice, education, research, and public service.
Position Summary
This full-time Research Specialist will function as part of a developing team of scientists whose overall goal is to advance public health by integrating epigenetics, developmental therapeutics, and clinical pharmacology into clinical and translational research that optimizes treatment strategies for hematology/oncology patients. The position will be assigned to the laboratory of Dr. Daniel Crona at the UNC Eshelman School of Pharmacy, in the Division of Pharmacotherapy and Experimental Therapeutics. The successful candidate will be involved with some research design/evaluation and will support activities related to laboratory operations, handling and curation of biological materials together with data collation and analysis of experiments conducted in the laboratory. Specific details covering these activities are provided below.
Minimum Education and Experience Requirements
Bachelor’s degree in a discipline related to the area of assignment; or equivalent combination of training and experience. All degrees must be received from appropriately accredited institutions.
Required Qualifications, Competencies, and Experience
Baccalaureate degree (BA or BS) required in molecular biology, pharmacology, biochemistry, or equivalently relevant major. 
Demonstrated experience with molecular biology techniques, including cell culture, DNA/RNA preparation and cloning, cell transfection, Western blotting, genotyping (e.g. TaqMan, Sanger sequencing, SNP chips, next-generation sequencing, etc.), reporter gene assays, PCR and qPCR, and siRNA knockdown. Experience with gene editing technologies (e.g., CRISPR/Cas9) is required. Demonstrated competency in data analysis and interpretation is also required. Preference given to candidate with experience using statistical software. \
Ability to plan and execute functional assays of genetic variants with minimal supervision. Troubleshooting of both experimental and instrumental technical issues.
Ability to accurately document laboratory experiments, analyze results, and evaluate data. Experience in preparing scientific reports and contributing to the preparation of grants, manuscripts, and media (posters, slides) for presentation at scientific conferences.
Maintenance and operation of specialized laboratory equipment. Training of other laboratory personnel in laboratory techniques. Experience working with cells in cancer-relevant model systems (e.g., 2D cell culture, spheroids, in vitro patient-derived xenografts, and/or organoids) is required. 
Effective communicator with excellent verbal and written communication skills. Demonstrated evidence of scientific publications and presentations will be viewed favorably.
Preferred Qualifications, Competencies, and Experience
Demonstrated experience with molecular biology techniques and theory, including: cell and tissue culture, DNA/RNA preparation and cloning, cell transfection, Western blotting, genotyping (e.g. TaqMan, Sanger sequencing, SNP chips, next- generation sequencing, etc.), reporter gene assays, PCR and qPCR, and siRNA knockdown.
Experience working with mice in cancer-relevant model systems (e.g., xenografts, syngeneic models, GEMMs) is highly desired. 
Prior experience with transcriptomics and proteomics analysis is desirable but not essential. 
Experience with additional gene editing technologies (e.g., deactivated Cas9, CasX, ZNFs) is highly desired. 
Familiarity, or ideally experience, with RNA-seq, ChIP-seq (or CUT&RUN) and/or ATAC-seq is highly desired.
Required Licenses/Certifications
Special Physical/Mental Requirements
Campus Security Authority Responsibilities
Not Applicable.
Position/Schedule Requirements
Special Instructions
Quick Link https://unc.peopleadmin.com/postings/280657

Contact Information


Office of Human Resources Contact Information
If you experience any problems accessing the system or have questions about the application process, please contact the Office of Human Resources at (919) 843-2300 or send an email to [email protected]
Please note: The Office of Human Resources will not be able to provide specific updates regarding position or application status.
Equal Opportunity Employer Statement
The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran.

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