Research Scientist, Senior (Center for Innovation in Brain Science)

The laboratory of Dr. Fei Yin in the Center for Innovation in Brain Science (CIBS) is currently seeking a research scientist to work on research projects related to mitochondrial dysfunction, lipid metabolism and metabolic reprogramming in Alzheimer’s disease and other neurodegenerative diseases.

Ongoing research in the Yin lab focuses on investigating the cell type-specific role of mitochondria and mitochondrion-derived signals in the onset and progression of Alzheimer's disease, their interaction with peripheral metabolic organs, as well as the development of novel therapeutics by targeting these pathways. The successful candidate should have strong background and demonstrated research experience in the areas of neuroscience, molecular and cell biology, and/or endocrinology, be able to perform research independently and collaboratively, and be comfortable and efficient in a fast-paced and growing research environment.

Outstanding UA benefits include health, dental, and vision insurance plans; life insurance and disability programs; paid vacation, sick leave, and holidays; UA/ASU/NAU tuition reduction for the employee and qualified family members; retirement plans; access to UA recreation and cultural activities; and more!

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• Plan, design, manage, and carry out innovative research projects related to neurodegenerative diseases utilizing strong background and in-depth expertise in the areas of molecular biology and neuroscience.
• Perform experiments utilizing sophisticated molecular, genetic, cellular and imaging technologies in both rodent and cell models independently. Key techniques include rodent brain surgery, design and prepare viral vectors for gene manipulation in the brain, preparation of primary brain cell culture, and comprehensive metabolic characterization of rodent brain and brain derived cells.
• Develop and validate new rodent and cell models for discovery research and therapeutic development utilizing deep expertise in molecular biology and/or neuroscience.
• Analyze research data and provide interpretations using biostatistic tools and software.
• Write manuscript for peer-reviewed publication and participate in acquiring research funding including writing grant proposals.
• Present results at national and international scientific conferences.
• Share supervisory responsibility for graduate and undergraduate students by training new students and oversee day-to-day operation of their projects.
• Work collaboratively with other members and laboratories in CIBS using expertise as described above.
• Additional duties as assigned.

Knowledge, Skills and Abilities:

• Demonstrated ability to independently prepare technical reports, graphics and manuscripts.
• Demonstrated productivity with publications in related field.
• Knowledge of primary cell culture and other general cellular and molecular biology techniques.

• Bachelor's degree or equivalent advanced learning attained through professional level experience required.
• Five (5) years of relevant work experience, or equivalent combination of education and work experience.

• Ph.D. in Molecular Biology, Cell Biology, Pharmacology, Neuroscience, or related field.
• Strong background and research experience in molecular biology and neuroscience.
• Strong rodent-related experience, including animal model development and maintenance, rodent surgeries and treatment, and behavioral, electrophysiological, and biochemical analyses of rodent models.
• Previous experience in the design, modification and construction of plasmids, vectors and viral deliveries for genetic manipulations in rodent and cell models.