RESEARCH SCIENTIST 2

As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem solving skills and dedication to build stronger minds and a healthier world.

UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty.

The Department of Medicinal Chemistry has an outstanding opportunity for a Research Scientist Engineer 2.  Research project supported by this position investigates virus structure and function so as to understand how viruses infect cells and how they can be targeted with vaccine-elicited responses.

This will be a 100% FTE appointment that requires expertise in cell culture, protein expression and purification, DNA cloning and site-directed mutagenesis. This position requires the ability to effectively perform research and take responsibility for assuring quality, cost effectiveness and timeliness for large size projects.

The successful applicant will join a research project at the interface of biochemistry, structural biology, biophysics, and vaccine design.  Our work focuses on structural and functional studies of influenza virus, Sars-CoV-2, and HIV cell entry machinery with translational applications in development of vaccines and virus inhibitors. The research is highly interdisciplinary and collaborative, which provides the opportunity to interact with scientists from different fields. In addition, the individual will have the opportunity to gain experience in advanced mass spectrometry, electron microscopy, spectroscopy, and virology.

Responsibilities

Manage general lab functions and supplies. Culturing HEK293 cells as well as carry out protein expression and purification. The scientist will also support other projects in the lab involving extracellular vesicle isolation, molecular biology, cloning, mutagenesis, biochemical and biophysical characterization such as by biolayer interferometry, Western Blot, ELISA, SDS-PAGE, electron microscopy, dynamic light scattering and other complementary methods. Another one of the responsibilities will be to help screen samples the lab receives from collaborators for homogeneity and sample condition/quality. In addition, the scientist will assist with general lab functions including making solutions, weighing reagents, making buffers, setting up laboratory apparatus and instruments, reading and recording instrument data, keep laboratory records, and taking part in preparing results for publications.

The position will also include laboratory managerial duties. Responsibilities include but are not limited to: directing purchasing, organizing critical lab functions, and assisting with strategic decision making.

Main research responsibilities include: