Research Investigator - Beyaz Lab

Cold Spring Harbor Laboratory (CSHL) invites applications for a Research Investigator in the laboratory of Dr. Semir Beyaz. A successful candidate for this position will have completed PhD and postdoc training in biomedical sciences, preferably in cancer biology, stem cell biology, epigenetics, metabolism, microbiome and/or immunology. We are looking for an experienced and highly motivated scientist to join a collaborative team of scientists in our lab on developing novel approaches to mitigate toxicity and enhance efficacy of cancer therapeutics by modulating nutrient metabolism. This exciting project is in collaboration with a leading US-based venture capital firm and biotech company. The successful candidate will have the opportunity to develop new skills in basic science and learn about the process of translating discoveries from bench to bedside.
The Beyaz lab aims to understand how nutrients and metabolism influence cellular networks that govern tissue regeneration, cancer and immunity. We dissect the precise mechanisms of how reciprocal interactions between tissue stem cells, immune cells and the microbiome affect tissue fitness or cancer outcomes. We utilize state-of-the-art experimental and computational approaches to integrate genetic, epigenetic, metabolism and microbiome data to identify causal targets that can be therapeutically exploited. To assess therapeutic potential of our discoveries, we have established a comprehensive and inclusive biobank with tissue specimens, autologous patient-derived organoids and immune cell co-culture systems from patients across diverse ancestries. The successful candidate will have access to all of these resources in the Beyaz lab and work in partnership with the biotech company to develop effective cancer therapies with minimal toxicity to host.

Education: PhD in biomedical sciences, ideally with additional postdoc experience in cancer biology, stem cell biology, epigenetics, metabolism, microbiome and/or immunology.
 
Skills and experience: The ideal candidate should have significant experience in molecular biology and mouse models of cancer. Having publications in the fields of metabolism, immunology, stem cell biology, epigenetics or cancer therapeutics will be an advantage.
 

How to Apply: 
If you are passionate about molecular biology and eager to contribute to groundbreaking research, we encourage you to apply for this exciting opportunity. Please submit an online application here: Position 965. In addition, candidates should e-mail their application to [email protected] as a single pdf file with subject: Research Investigator Application. The application file should include: (1) CV with the publication list, (2) a brief description of research interests, (3) contact information for three references. We look forward to reviewing your application. 
 
Environment
Cold Spring Harbor Laboratory is a world-renowned biomedical research institution in New York. It has shaped contemporary biomedical research and is the home of eight Nobel Prize laureates. Cold Spring Harbor Laboratory provides a highly dynamic and interactive research environment and also a unique opportunity of timely exposure to advances in various biomedical research fields and of interaction with a broad range of researchers from all over the world through its renowned Meetings and Courses program. We believe that science is for everyone. We have had researchers with a variety of backgrounds and believe in the importance of diversity, equity, and inclusion.
 
Compensation and Benefits
Our employees are compensated in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our CSHL Benefits sites to learn more. The salary range for this role is $82,700-95,000 per annum. The salary range and/or hourly rate listed is a good faith determination of potential base compensation that may be offered to a successful applicant for this position at the time of this job advertisement and may be modified in the future. When determining a base salary and/or rate, several factors may be considered as applicable (e.g., years of relevant experience, education, credentials, and internal equity).
 
CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. VEVRAA Federal Contractor