Research Associate II - Metabolic Research

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

A Research Associate II position is available in the laboratory of Dr. Ke Ma.  The Ma lab applies state-of-the-art circadian biology, molecular and cellular biology approaches to diabetes and obesity research, with an ultimate goal to unravel circadian etiologies underlying the current epidemics of metabolic diseases for targeted therapeutic interventions. We have a unique research program in deciphering the mechanistic underpinnings of circadian clock control in metabolic tissue development, growth and functional capacity, focusing on skeletal muscle and adipose tissue biology. Recent projects expand into drug screening platforms to identify clock-targeting small molecules for metabolic disease applications. 

As a successful candidate, you will:

·         Utilize biochemical and molecular biology approaches combined with genetic animal models, specific research directions in the lab include

o   Genetic and epigenetic signaling networks mediating circadian clock nutrient-sensing function in adipose tissue and skeletal muscle

o   Circadian clock regulation of skeletal muscle growth and metabolism

o   Novel signaling mechanisms in core circadian clock regulation

o   Developing small molecule clock-modulators for metabolic disease therapy.

Qualifications:

·         Bachelor’s degree.  Masters degree preferred with a strong interest to pursue metabolic research

·         2+ years of related research/laboratory experience with a Bachelor’s degree or 1+ year related research/laboratory experience with a Master’s degree.

·         Hands-on experience with cell culture and in vivo animal model research is preferred.

·         Proficiency with basic biochemical techniques, molecular biology skills and cell culture systems.

·         Experience working with cell culture and rodent models. Lab technical expertise in biochemistry, molecular biology, cell biology animal physiology are desired

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