The Research Assistant will be tasked with collecting blood samples from patients and bringing the samples to the lab. Several of the experiments are time sensitive, thus it is imperative for the research team to collect the samples in a timely fashion and begin some of the tests within minutes. Inaddition to acting as the liaison between the clinical setting and the laboratory for the team,the Research Assistant will perform some of the laboratory measurements, be involved with data collection, analysis, and interpretation.
The Research Assistant will write abstracts to present at national meetings,and papers for publication in peer-reviewed journals. Experience with writing papers and responding to the peer review process is required. A track record of previous publications is preferred for this position.
Assisting with the SNOHb, NO, and Nitrite experiments in the lab.We will need to be running experiments simultaneously thus experience with these lab methods is crucial to obtaining high- quality results. The Research Assistant's role will vary day-to-day depending on the volume of samples collected and availability of resources/ equipment.
Assisting with determining the oxygen dissociation curves for RBC samples. This entails operating the Hemox-Analyzer. Assisting with the deformability, aggregation,and adherence experiments. The Research Assistant will be trained to use the Rheoscan ektacytometer and several other instruments. Assisting with the oxidative stress experiments comparing the stored versus salvaged RBCs. The esearch Assistant will be operating the instruments measuring fluorescent heme degradation products.
Bloodless Medicine and Surgery Clinical Service:
The position involves following patients on our service who do not accept blood transfusion. These patients receive special treatments as alternatives to transfusion. These patients also require special blood conservation measures such as autologous blood salvage, iron and EPO therapy, minimizing blood loss due to phlebotomy, and tolerating lower hemoglobin levels without transfusing.
The person who fills this position will track clinical outcomes, laboratory values, and special treatment modalities to determine whether patients receiving Bloodless care do as well, better, or worse than patients who accept transfusion.The Research Assistant will attend team meetings to learn and offer input to optimize patient care without transfusing blood.
The ability to communicate well with patients and their family members is critical. A good understanding of compassion and empathy for sick patients and their family members will be important (a good bedside manner).
Database Review on Blood Utilization:
We maintain three separate databases that track blood utilization across the Johns Hopkins Hospital, and these databases have now been expanded to cover the entire Johns Hopkins Health System (all five hospitals).
To update and curate these databases requires programing skills with software applications such as SAS,JMP, Excel,and Stata. Understanding of statistical analysis using continuous, dichotomous, and ordinal variables will be required and this entails performing uni variate and multivariate statistics, along with multiple linear and logistic regressions. Graphic display of findings, including table and figure generation for publications will be required. Manuscript writing and editing is also a skill required for this position.
Collaboration with members of other departments will be required in order to merge databases and examine the relationships between blood transfusion and outcomes. We will be using relational databases and some SQL and R programing language code will be used, but will be taught with training on the job or we will obtain help with these applications from the clinical research center at ACCM