Radiochemistry Technologist

Located on the University of Pittsburgh Main Campus, the PET Research Center benefits from its central location to the major clinical and research activities of the institution. Presently, the center comprises a dedicated full time research staff of approximately 25, including ten full-time Radiology faculty members. The staff also includes nuclear medicine fellows, post-docs and radiochemistry technicians. The PET Research Center maintains an array of dedicated research scanners and equipment. Although the emphasis of the research facilities is on neuroimaging initiatives, a growing component of research in oncology and other systemic disorders continues to diversify its research efforts.

Under the general direction of the Radiochemistry Supervisor, perform or assist in the production of radiopharmaceuticals for experimental PET studies. Perform quality control analysis of radiopharmaceuticals used in positron emission tomography (PET) scans and analysis of plasma samples for trace amounts of radiolabeled metabolites. Perform separation and purification of precursors used for radiolabeling.

Essential Functions 

Radiolabel routine radiopharmaceuticals. Perform quality control tests associated with the preparation of radiopharmaceuticals. These tests include determination of sterility, apyrogenicity, chemical purity, radiochemical purity, radionuclidic purity, and specific activity. Perform Analysis and quantification of radiolabeled metabolites in plasma samples following the injection of short-lived radiotracers in PET studies. The metabolite analyses involve the separation of plasma from whole blood, fractionation of various radiolabeled metabolites in the plasma using solvent extraction techniques, and identification of metabolites using high performance liquid chromatography (HPLC), thin layer chromatography (TLC), or gas chromatography (GC) methods. Conduct identification, separations, and quantitation of compounds and radionuclides utilizing HPLC, TLC, GC, NMR, UV, IR, and gamma-ray spectroscopy.

Must be able to sit or stand for long periods of time.

The University of Pittsburgh is committed to championing all aspects of diversity, equity, inclusion, and accessibility within our community. This commitment is a fundamental value of the University and is crucial in helping us advance our mission, which includes attracting and retaining diverse workforces. We will continue to create and maintain an environment that allows individuals to discover, belong, contribute, and grow, while honoring the experiences, perspectives, and unique identities of all.

The University of Pittsburgh is an Affirmative Action/Equal Opportunity Employer and values equality of opportunity, human dignity and diversity. EOE, including disability/vets.