Details
Posted: 23-Feb-24
Type: Full-time
Salary: Open
Categories:
Other Staff/Administrative
Staff/Administrative
Internal Number: R98242
Postdoctoral Scholar Position
Job detail: As a postdoctoral scholar, you will conduct independent research under the guidance of a scientific mentor, focusing on the domains of ovarian and endometrial cancer research. Your research will center on elucidating the mechanisms through which extracellular vesicles secretion mediates high-grade serous ovarian cancer (HGSOC) and endometrial cancer progression, metastasis and platinum resistance. This knowledge is crucial for the development of innovative strategies for both prevention and targeted treatments. Additionally, our current project is focused the obesity is associated endometrial cancer-related mortality and obese patients have worse disease survival, highlighting the urgent need to identify involved mechanisms and novel molecular targets that contribute to the progression of EC. We are developing safe antineoplastic compounds that selectively target tumor cells while protecting normal cells and tissues, synergizing with existing platinum-based chemotherapy regimens. The ultimate goal of this proposed research is to identify how obesity associated endometrial cancer regulating EVs secretion with oncogenic proteins and its contribute to EC progression and evaluate the EVs inhibitor as a safe therapeutic drug for EC.
Experience: Doctoral Degree Program in Biomedical Science: Applicants must have a PhD and either completed research work during their doctoral studies or gained 1-2 years of postdoctoral experience in the field of cancer research. Additionally, they should demonstrate a high level of competence and productivity as researchers. This typically involves having authored publications of significant interest and value to the field, as evidenced by favorable reviews, citations in the work of others, presentations of papers at professional societies, and contributions such as new designs, or techniques that hold material significance in advancing our ongoing research efforts.
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About The Ohio State University
The Ohio State University is a dynamic community of diverse resources, where opportunity thrives and where individuals transform themselves and the world. Founded in 1870, Ohio State is a world-class public research university and the leading comprehensive teaching and research institution in the state of Ohio. With more than 63,000 students (including 57,000 in Columbus), the Wexner Medical Center, 14 colleges, 80 centers and 175 majors, the university offers its students tremendous breadth and depth of opportunity in the liberal arts, the sciences and the professions.
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