Our research, at the intersection of physics and biology, aims to understand how cellular signal processes are regulated on different hierarchical length-scales through the application and further development of single molecule and super-resolution microscopy techniques. We employ recently developed quantitative super-resolution microscopy in cells to resolve signaling complexes and organelles below the optical diffraction limit and measure their biomolecular composition. This characterization allows us to detect changes as organelles mature and to follow spatial re-arrangements of signaling proteins in response to stimuli. A particular focus of our lab is to investigate if and how such spatial re-arrangements can modulate the signaling strength of pathways. In addition, we use optogenetic tools to manipulate cell signaling.
We are seeking a strong postdoc candidate whose interests and experience lies within our field of research. The research will involve cloning, molecular biology and cell culture to tag and modify proteins in yeast and mammalian cells. Furthermore, advanced data analysis will be necessary to extract relevant information from single molecule and super-resolution fluorescence microscopy studies of the created cell lines.
The candidate should have a Ph.D. in biophysics or a closely related field by the beginning of the appointment. Extensive experience in cloning, molecular biology, and fluorescence microscopy are expected; a special focus on super-resolution microscopy and single molecule imaging is preferred. The candidate will be expected to independently lead his or her research project and train undergraduate/graduate students in laboratory and microscopy techniques. Clear and efficient written and oral communication skills are therefore required as well as a good integration into our lab.
Postdoc Position – Single Cell Transcriptomics Of The Human Embryonic Kidney, Leiden University, Netherlands, about 13 hours ago
The Faculty of Science and the Leiden Institute of Physics are looking for applicants for a Postdoc position – single-cell transcriptomics of the human embryonic kidney (1.0 fte) Vacancy number 17...
Research Specialist Pharmacology (Job Id #81279), University of Illinois, United States, about 9 hours ago
Purification of lentiviruses, retroviruses and adenoviruses, dissecting function of Src family protein tyrosine kinases and tyrosine phosphatases Shp2 and VE-PTP in regulation of endothelial cell-...
Non Neuron Optogenetics Or Cancer Research, National Institutes of Health, United States, 3 days ago
Position Description: Postdoctoral Fellow positions (can join anytime between 2017 July to 2018 March) are available in Lee laboratory at Johns Hopkins University (Baltimore, MD). These positions ...
Post Doctoral Associate, University of Massachusetts Medical School, United States, 1 day ago
Postdoctoral position in applied developmental immunology We seek a talented and motivated postdoc to join our team in Program in Molecular Medicine and Diabetes Center Of Excellence at the Univer...
Postdoc Or Contract Biologist, National Institutes of Health, United States, 3 days ago
Position Description: The position will be at the National Institutes of Health, National Eye Institute, Division of Intramural Research, Section on Epithelial and Retinal Physiology and Disease, ...
Post Doctoral Associate, University of Maryland, United States, 10 days ago
Position Summary/Purpose of Position: A postdoctoral position is available to investigate respiratory virus-host interactions, with an emphasis on innate defense. Our lab works independently and c...