Postdoctoral Research Associate

Updated: about 1 month ago
Location: Dover, DELAWARE


General Description of the Position

The Post-Doctoral Associate will work closely with the Principal Investigator using biochemical and molecular biology techniques to develop targeted small protein therapeutics that aim to induce an immune response by targeting specific proteins in cancer cells.


Essential Functions & Required Knowledge, Skills and Abilities

The following are the functions essential to performing this job:
1. Carry out experiments to develop and validate small proteins that have high affinity and selectivity for cancer cells 
2. Assist with preparation of manuscripts for submission to scientific journals and conferences 
3. Performs literature studies and writes technical reports 
4. Assist in training and mentoring lab personnel, including graduate and undergraduate students. 
5. Organizes and attends research group and sub-group meetings. 
Other Functions 
Individual in this job may be assigned one or more of the following tasks on a rotating or as-needed basis:
1. Oversees image analysis projects and works with other lab members 
2. Presents the lab’s research work at regional, national, and international scientific meetings and conferences 
3. Attends workshops/seminars on protein engineering and discovery 
4. Attends workshops/seminars on computational aided drug discovery 

Required Knowledge, Skills, and Abilities 

The individual in this job must possess these skills and abilities or be able to explain and demonstrate that they can perform the essential functions of the job, with reasonable accommodation, or using some other combination of skills and abilities: 
1. Demonstrated experience in protein engineering, expression, purification, and biochemical characterization 
2. Demonstrated experience in cell-based assays such as ELISA , flow cytometry binding, BLI 
3. Expertise in molecular biology techniques such as cloning, PCR, mutagenesis, DNA extraction, gel electrophoresis 
4. Knowledge of protein/antibody discovery and optimization using in vitro display (such as phage or yeast) technology 
5. Knowledge of two-hybrid assay screening, focusing on studying molecular interactions, such as protein-protein, protein-DNA, and protein-RNA interactions 
6. Strong analytical and problem-solving skills 
7. Excellent communication and collaborative abilities 
8. Works well as part of a diverse, multicultural tea


Qualification Standards

1. Education: PhD (required) in Chemistry, Biochemistry, Biology, Molecular Biology or related area. 
2. Experience in expression, purification, characterization and optimization of recombinant proteins. 
3. Experience with design, execute, and troubleshoot SPR and BLI-based assays, including binding kinetics, blocking, affinity, competition, and epitope binning 
4. Other preferences: Familiarity with de novo protein design


Performance Standards & EEO Statement

The criteria for evaluation in this position include, but are not limited to, the following: 
1. Demonstrates knowledge of the DSU Fundamentals 
2. Demonstrates ability to manage day-to-day operations of the project per directives of PI

EEO Statement

Delaware State University is an equal opportunity employer committed to fostering a diverse and inclusive academic global community. The University is dedicated to enhancing diversity and inclusion in all aspects of recruitment and employment. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity, gender expression, national origin, ancestry, citizenship status, physical disability, mental disability, medical condition, military and veteran status, marital status, pregnancy, genetic information, or any other characteristic protected by state or federal law. The University is committed to achieving a diverse faculty and staff and encourages members of underrepresented groups to apply.

Equal opportunity employer/program'' and “auxiliary aids and services are available upon request to individuals with disabilities''.