LAB RESEARCH ANALYST II

This Position is Grant Funded

School of Medicine

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

LAB RESEARCH ANALYST II

Macintyre Lab – Duke Human Vaccine Institute

The Duke Human Vaccine Institute (DHVI), an international leader in the fight against major infectious diseases, is seeking a highly motivated individual for the position of Laboratory Analyst II.Investigators at the DHVI conduct basic and translational research to develop novel vaccines, therapeutics and diagnostics.

The Duke Regional Biocontainment Laboratory (RBL) is a division of the DHVI and supports a wide portfolio of research programs. The RBL has three collaborative core units: Immunology, Virology, and Microbiology. The Lab Research Analyst II will work with the RBL Immunology team and Duke Investigators to plan, run and analyze flow cytometry assays plus other immunoassays such as ELISpot and ELISA.

The ideal candidate will have a Bachelor’s degree in biological science or a related field. Laboratory experience in immunology, cell biology, molecular biology or related field is required. Previous experience with flow cytometry and/or ELISpot is highly preferred.

RESPONSIBILITIES:

• Prepare samples for and perform flow cytometry (including techniques such as intracellular cytokine staining and multi-parameter surface marker staining).
• Prepare samples for and perform ELISPot
• Analyze flow cytometry data using specialized software (e.g. FlowJo) and prepare tabular and graphical summaries for reporting to collaborators.
• Assist Investigators and Immunology Unit leadership with the design and optimization of flow cytometry staining panels.
• Prepare and process specimens for immunological procedures other than flow cytometry, including but not limited to Luminex and ELISA.
• Train laboratory members in flow cytometry, ELISPot and other techniques.
• Confer with Immunology Unit leadership to review work assignments and develop plans for experiments.
• Complete and maintain electronic documentation of research activities in real time.
• Manage and complete all assigned tasks/projects in accordance with standard operating procedures (SOP) and in full compliance with all safety protocols.
• Develop, write and maintain SOP.
• Attend all required training.

• General laboratory maintenance including but not limited to: laboratory organization, preparation of solutions, waste processing, ordering/preparation/stocking of consumables and reagents, routine equipment calibration, maintenance of accurate sample inventories.
• Perform additional duties as requested by Immunology Unit Leadership and RBL/DHVI leadership.

The successful applicant must be eligible for and willing to:

• Complete necessary training and certification for independent work at Biological Safety Level 3 (BSL3).
• Work with infectious biological agents (viruses and bacteria) handled at BSL2 and BSL3.
• Comply with vaccination requirements.
• Complete Tier 1 Select Agent registration.

REQUIRED QUALIFICATIONS AT THIS LEVEL:

• Education/Training: Work requires a bachelor's degree in botany, biology, zoology, psychology or other directly related scientific field.
• Experience:Work requires four years of research experience. A related master's degree may offset required years of experience on a 1:1 basis, e.g., a two-year master's degree in lieu of two years of experience. OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE.

PREFERENCES:

• Excellent interpersonal, problem-solving, communication and organizational skills. 
• Ability to work independently and as part of an interdisciplinary team. 
• Willingness and ability to work on multiple projects simultaneously. 
• Analytical skills to resolve problems requiring the use of scientific, mathematical, or technical principles.

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

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Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.