Research Fellow in Cancer Immunology

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Antibody and Vaccine Group, Centre for Cancer Immunology, University of Southampton, Faculty of Medicine, School of Cancer Sciences 

Monoclonal antibodies (mAb) are effective treatments for cancer, albeit with considerable potential for further improvement. The Antibody and Vaccine Group based in the Centre for Cancer Immunology in Southampton has a strong track-record in basic and translational immunology relating to developing therapeutic mAb for clinical examination. Over the last decade they have begun to better appreciate the role of myeloid cells in determining the efficacy of antibody therapeutics

Now, in collaboration with Boehringer Ingelheim they are beginning a new project aimed at targeting these myeloid cells to overcome immune suppression and elicit better therapy. Profs Mark Cragg and Stephen Beers, alongside Dr Stephen Thirdborough, aim to leverage the significant antibody capabilities and expertise at Boehringer to develop new and more effective antibody reagents for cancer patients. The current opportunity is for a research fellow to join the team to help discover and augment mAb capable of manipulating myeloid cells to elicit powerful anti-tumour responses, with the potential for the discovery of novel anti-cancer therapeutics,

You will be motivated, educated in a relevant subject area and have practical laboratory experience of antibody biology and antibody engineering. Experience of myeloid cell biology would be an advantage but is not critical. You will work alongside a new PhD student to deliver novel insight in this exciting area, with the aim to identify and develop reagents for clinical translation. 

The position is full-time and for 36 months in the first instance.

Informal queries should be directed to Professor Mark Cragg ([email protected] )

Details about the Antibody and Vaccine Group, Cancer Sciences and Centre for Cancer Immunology can be found at https://www.southampton.ac.uk/research/institutes-centres/antibody-vaccine-group ;  https://www.southampton.ac.uk/research/groups/cancer-sciences ; https://www.southampton.ac.uk/research/institutes-centres/centre-for-cancer-immunology

*Applications will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification.  The title of Research Fellow will be applied upon completion of PhD.  Prior to the qualification being awarded the title of Senior Research Assistant will be given. 

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Apply by 11.59 pm GMT on the closing date. For assistance contact Recruitment on +44(0)2380 592750  or [email protected] quoting the job number.