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School of Medicine, Translational Medical Sciences
Location: University Park
Salary: £30,487 to £39,347 per annum, (pro rata if applicable) depending on skills and experience (minimum £33966 with relevant PhD).
Closing Date: Wednesday 13 March 2024
Interview Date: To be confirmed
Reference: MED514923X1
Applications are invited for the role of Research Associate/Fellow to join the unit of Translational Medical Sciences within the School of Medicine. The role will support our recently awarded BBSRC strategic Longer and Larger project, GlycoWeb. This multi-partner project includes research groups from The University of Nottingham, Liverpool University, Manchester University, and the Francis Crick Institute and we additionally have international (USA and Denmark) and commercial partners (InterReality Labs) as part of the team.
The team assembled for this programme will apply a diverse set of approaches to address the fundamental gaps in knowledge on Glycosaminoglycans (GAGs) using an ambitious multidisciplinary approach, integrating analyses at the transcriptional through to the multicellular level. Linking with international centres of excellence in Denmark and the USA, as well as a commercial partner expert in the application of virtual reality to data sharing and interrogation, ensures that the team can work at the forefront of technological advances. The posts include opportunities for working visits to partner labs, dependent on the applicant’s personal situation and availability for travel.
Candidates must hold a PhD (or be near to completion of a PhD or equivalent) in biochemistry, cell biology, glycobiology, matrix biology or a related area. Candidates should also have experience of a range of techniques, with a focus on 3D cell culture models, biochemical analysis, imaging and image analysis. The position will involve stem cell biology, immunocytochemistry, ToF-SIMS, and glycosaminoglycan analysis. It would be advantageous to have experience of in vitro 3D co-culture model development, mass spectrometry, matrix biology, structural analysis, and a good understanding of glycobiology. You will work within a highly skilled, collaborative, and exciting research team, making use of state-of-the-art 3D models of development known as gastruloids to determine how changes in GAG structures affect the signalling pathways driving early development.
There are 2 full-time (36.25 hours) posts available, offered as fixed-term contracts to 31st December 2028. Arrangements for job share may be considered. Requests for secondment from internal candidates may be considered on the basis that prior agreement has been sought from both your current line manager and the manager of your substantive post, if you are already undertaking a secondment role.
Informal enquiries may be addressed to Professor Cathy Merry, [email protected]. Please note that applications sent directly to this email address will not be accepted.
Further details:
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