23 Mar 2024
Job Information
- Organisation/Company
KINGS COLLEGE LONDON- Research Field
Literature
Chemistry- Researcher Profile
Recognised Researcher (R2)
Established Researcher (R3)- Country
United Kingdom- Application Deadline
2 Apr 2024 - 00:00 (UTC)- Type of Contract
Other- Job Status
Full-time- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
Job description
Context
This position is part of a prestigious Cancer Research UK Early Detection and Diagnosis Award to King’s College London. The aim of the project is to evaluate an oncogenic receptor tyrosine kinase, which is upregulated in aggressive malignancies such as non-small cell lung cancer (NSCLC), as a prospective biomarker for early NSCLC detection and monitoring. This will be achieved by implementing parallel tracks of technical, biological, and clinical validation following the biomarker/imaging biomarker roadmap strategy. This position is specifically dedicated to the development of this early detection biomarker toolbox for both blood-borne biomarker analysis and non-invasive whole-body PET imaging.
Role
The successful candidate will have a strong interest in cancer biomarker research and will be part of a multi-disciplinary team of cancer researchers, cell biologists, and imaging scientists. The post holder will be designing and performing a variety of in vitro, in vivo, and ex vivo experiments in close collaboration with other team members. Importantly, it is a requirement of this project to collaborate with existing teams of scientists with diverse backgrounds inside and outside the department, in particular with colleagues providing specialist tumour models, antibody developers, and animal technicians. The post holder will have access to cutting-edge technologies including antibody validation platforms, patient-derived tumour models, and quantitative whole-body tumour and ImmunoPET imaging alongside access to a variety of state-of-the-art King’s facilities such as those for flow cytometry, advanced microscopy, and preclinical tumour models. The role involves work at different CR-UK City-of-London Centre Campuses as required by experimental requirements.
This post will be offered on a fixed-term contract for 34 months initially, with further extension of another 2 months.
This is a full-time post - 100% full time equivalent.
Key responsibilities
- To perform in vitro, in vivo, and ex vivo experimentation required to validate blood-borne and imaging-based cancer biomarkers.
- To perform in vivo and ex vivo experimentation with patient-derived and animal tumour models.
- To work with macroscopic in vivo imaging technologies including PET imaging.
- To work with various microscopic brightfield and fluorescence imaging technologies.
- To work with immunological methods including but not limited to multi-parameter flow cytometry and immunoblotting.
- To work independently on a defined project and to consult when appropriate.
- To design, implement, and manage new and existing project parts.
- To collaborate and support scientific collaboration consistent with the post in the interest of the project team.
- To be fully familiar with relevant scientific literature.
- To take responsibility for regularly constructing manuscripts/reports or parts thereof in excellent written English for publication in high impact journals.
- To participate and present work regularly in team meetings and conferences.
- To maintain accurate, up-to-date records of work and its findings.
- To work at various CRUK CoL sites as required for optimal project progress.
- To supervise and train students and junior staff.
- Any other necessary duties consistent with the nature and grade of the post, including participation in shared roles of laboratory management and maintaining a safe laboratory environment.
Skills, knowledge, and experience
Essential criteria
Desirable criteria
Further information
Interviews are expected to be held on Thursday 25th April 2024 with candidates being informed around two weeks before the scheduled interview.
This post is subject to Occupational Health clearance.
Requirements
Additional Information
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- KINGS COLLEGE LONDON
- Country
- United Kingdom
- City
- London (Central)
- Geofield
Where to apply
- Website
https://www.timeshighereducation.com/unijobs/listing/368014/postdoctoral-resear…
Contact
- City
London (Central)
STATUS: EXPIRED
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