We are seeking a new member of the Genomics of Inflammation laboratory (led by Prof Irina Udalova) with responsibility for carrying out research into the role of myeloid immune cells in the pathophysiology of inflammatory diseases.
Myeloid cells are important players in inflammatory diseases, including vasculitis and arthritis. It has been recently increasingly appreciated that the localisation of myeloid immune cells in inflamed tissues is crucial for understanding their functions. Additionally, these cells can perform classical and non-classical immunological functions both contributing to pathology and reinstating homeostasis. The proposed project will study the impact of neutrophils and macrophages in both human and murine inflammatory conditions and their spatial localisation and functions.
In this role you will take responsibility for the planning and execution of high-quality research, ensuring the validity and reliability of data, at all times. You will test hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate. You will adapt existing and develop new scientific techniques and experimental protocol. You will be expected to contribute ideas for new research projects, contribute ideas for new research projects, and maintain an up-to-date awareness of relevant publications in the area of research.
To be successful in this role, it is essential that you hold a PhD degree (or near completion) in immunology, molecular and cell biology, or similar. You must have a strong background in innate immunity and inflammation. You must be able to demonstrate the capacity to deliver high-quality research outputs, as illustrated by a strong publication record in immunological journals. It is essential that you have experience in working with multiple imaging modalities, ranging from organ to subcellular imaging, as well as experience in advanced immunological and genomic techniques.
It is preferable that you have experience working with myeloid cells, and tissue imaging. It is desirable that you have experience in advanced in vivo models of inflammation, however this is not essential.
Due to the nature of the research at the Kennedy Institute of Rheumatology, this job will require additional security pre-employment checks:
• A satisfactory basic Disclosure and Barring Service check due to the nature of the work at the Kennedy
• University security screening (eg identity checks) due to the nature of the work at the Kennedy
This is a fixed-term, full time position from 1/5/2024 until 16/12/2024.
The closing date for this position is 12 noon on Thursday 21st March 2024. You will be required to upload a CV and supporting statement as part of your online application.
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