Postdoctoral Fellow

Location: The Francis Crick Institute, Midland Road, London

Short summary

A potential project is to understand the interplay between cell division and cell identity during human development, reprogramming and disease using hESC and organoid models.

In this project, some of the specific aims include but are not limited to:

• To use genome editing technologies to perturb the cell cycle-cell identity cross-talk
• To measure cell cycle dynamics during cellular transitions by state-of-the-art live cell imaging
• To integrate sequencing (OMICS) and imaging data sets

The successful candidate will have the opportunity to decide on the exact project(s) they want to undertake during their postdoc time in the lab. Specifics of different projects will be discussed with Dr Silvia Santos. The successful candidate can either choose one of these projects or decide to undertake a new, independent project within the lab’s interests.

Key Responsibilities

Postdoctoral Fellows will lead their own research project(s) and may contribute to other collaborative projects (both within the lab and with external collaborators). Postdocs within the lab are expected to contribute to an excellent lab culture and train (junior) colleagues. Postdoctoral fellows are encouraged to manage collaborative work with Science Technology Platforms at the Francis Crick Institute. The ability to work independently and as part of the team is essential. Excellent communication skills are essential. The postholder is expected to either already have some expertise in data analysis or be willing to learn while in the lab. Training will be available at the Institute and within the lab in programming languages such as R. The postholder will be responsible for maintaining very organised lab records and protocols. The postholder will be expected to present their work internally and encouraged to attend and present at national and international scientific meetings.

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

• If you are interested in applying for this role, please apply  via the ‘Apply’ button above.
• This is a rolling advert with no closing date
• All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.