Postdoc in Computational Structural Biology - Evolutionary-scale interpretation of protein functions in human gut microbiome (80-100%)

How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world's leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!

In Torsten Schwede's group, we use computational methods to model protein structures, analyse protein-ligand interactions, explore the effects of mutations on protein structure and function, and classify protein families on a large-scale. We also explore artificial intelligence to characterise the dark proteome and pioneer automated methods for uncovering unknown protein functions.

Within the SIB Swiss Institute of Bioinformatics, we develop SWISS-MODEL (https://swissmodel.expasy.org ), a widely used web-based platform for generating high-accuracy 3D models of protein structures and complexes for application in life sciences. We also develop the Protein Universe Atlas, a web resource designed to streamline the navigation through the extensive wealth of publicly available protein sequence and structure information.