Research assistant in microbiology

Our research focuses mainly on host-bacterial interactions, with projects ranging from bacterial regulatory systems to innate immune responses in the host. The main research program includes studies on the molecular epidemiology and pathogenesis of pneumococcal infections, from the clinical side to more basic approaches looking at host-pathogen interactions. In our group, you will be able to develop knowledge ranging from basic microbiology, bacterial regulatory systems and immune response of the host.

We are looking for a candidate to fulfil a temporary position working primarily on investigating the innate immune response to Streptococcus pneumoniae infection. The main goal is to dissect the pneumococcal factors involved in activating lung resident macrophages, to better understand their contribution to a protective immune response. The project will focus on generating mutant strains of S. pneumoniae, before investigating the immune response they induce in macrophages. Flow cytometry and ELISAs will be used to fully characterise the immune response. Moreover, maintaining a lab notebook with thorough and organized data, as well as oral and written communication in English of the results will be required.

Requirements for the position: 

• The successful candidate is preferably a MSc graduate, with laboratory experience in both microbiology and immunology, looking for a short lab project to gain further experience in laboratory work.
• Additionally, they have an understanding of microbiology theory and previous laboratory experience working with:
  • Bacteria, especially growth and culturing in BSL-2 level
  • Purifying pneumococcal genomic DNA
  • PCR techniques and extensive knowledge in cloning transformation and creating bacterial mutants
• Moreover, the candidate should have experience in conducting flow cytometry and using FlowJo analysis software
• The applicant should be methodical and organized in work and have good record keeping skills
• Successful applicants must have the ability to work both independently and collaboratively in a group and have excellent English communication skills, both oral and written

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.

Location: Solna

Birgitta Henriques Normark Group

Welcome to apply at the latest 2024-03-12

The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form. 

Permanent position is initiated by a six months trial period.