Postdoctoral Researcher in Transfusion Immunology

Updated: about 1 month ago

Do you want to contribute to top quality medical research?

This is a unique opportunity to work with and solve clinically relevant questions in a well-funded research group with close ties to Karolinska University Hospital. In our research group, we conduct translational research with a clear focus on the patient.

The Center for Hematology and Regenerative medicine, HERM, is a research unit within the Department of Medicine Huddinge with a focus on translational hematology and immunology. HERM is located in the NEO building and consists of a mix of clinical and preclinical research groups, each with a focus on clinically relevant questions in hematology, stem cell biology and immunology, including basic immunology, immunodeficiency and transfusion immunology.


Your mission

Your will work in a team together with Dr Roland Fiskesund in Professor Petter Höglund’s research group. You will be working with routine cell- and molecular biology techniques including flow cytometry, cell culture and PCR. You will use your previous bioinformatics and wetlab experience to elucidate gene regulation of NK cell education, particularly concerning SHP-1. You will also be involved in projects related to gene-regulation of pro- and anti-inflammatory phenotype in Neutrophils as well as production of CAR-Neutrophils for cancer treatment.

Our research group has close ties to the Department of Clinical Immunology and Transfusion Medicine at Karolinska University Hospital, where both Dr Fiskesund and Professor Höglund are physicians. We strive to apply cutting edge immunological methodologies to study and solve clinically relevant problems. Our goal is to improve cell-based therapies at the hospital, including transfusion of blood components and stem cell transplantations. Our projects are of a translational character and results can generally be quickly implemented in the clinic.

Your main responsibility will be to develop and conduct independent research projects at the postdoctoral level within the line of ongoing research in the group. The candidate is expected to provide expertise and constructive collaborative efforts into ongoing projects.


Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence within the fields of Transfusion Medicine. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

The applicant is expected to be a talented and highly motivated researcher and who plays a leading role in experimental design, experimentation, and presentation/publication of results. The candidate must be able to work within a team environment.

Duties and work tasks

  • Elaboration of scientific hypothesis, experimental design
  • Flow cytometry and other routine molecular biology work
  • Data Analysis
  • Presentation and publication of results 

Entry requirements, skills, and personal qualities

Qualification requirements

  •  PhD or with extensive previous research experience in Transfusion Medicine or Immunology
  • Excellent oral and written communication skills in English
  • Proficiency in Next Generation Sequencing
  • Profound knowledge in bioinformatics analysis, especially regarding gene regulation and gene expression.
  • Proficiency in cell sorting (FACS)

Skills that count in the assessment

  • Experience in using a variety of molecular biology technologies
  • Experience with Flow Cytometry
  • Experience working with primary cells Knowledge of Transfusion Medicine
  • First authorship papers in high-ranking, peer-reviewed journals

Personal qualities

  • Hard-working and driven Organized Self-directed and independent Creative Collaborative, team player

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location:
Flemingsberg

Department of Medicine
HERMS
Choose to work at KI – Ten reasons why

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply at the latest 12 June, 2024.

The application is to be submitted through the Varbi recruitment system.


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