Postdoctoral Researcher in skeletal stem cells

Karolinska Institutet (KI) is one of the world’s leading medical universities. Our vision is to advance knowledge about life and strive towards better health for all. KI accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at KI selects the Nobel laureates in Physiology or Medicine.

KI offers a unique environment in which to work with innovative researchers and state-of-the-art facilities to perform basic, pre-clinical and clinical research. We offer an engaging and international research environment where you will have the opportunity to contribute to high quality research at a leading international institution. 

Division

The role is based at the Department of Women's and Children's Health. The successful candidate will explore the cellular and molecular mechanisms governing skeletal growth during physiology and pathology in vivo using mouse models, ex vivo using human biopsies, and in vitro using cell culture models.

• Develop and implement research projects in conjunction with
• PI Independently design, conduct, execute and analyse experiments
• Actively follow and implement the scientific literature
• Write and edit manuscripts
• Actively participate in collaborative lab and project meetings
• Support our collaborative research environment and guide colleagues with technical and operational aspects of scientific research
• Assist in laboratory requirements (eg. training and compliance)
• Present work at international conferences

The successful candidate will apply and develop protocols including in vitro and ex vivo culture (2D and organoid), size exclusion chromatography, nanoparticle tracking analysis, flow cytometry, super-resolution microscopy, ex vivo organ culture, spatially resolved transcriptomics, histological and histochemical staining, immunofluoresence, electron microscopy and other relevant technologies, as applicable. The successful candidate will be given the opportunity to work towards scientific independence.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

We are looking for an enthusiastic person with a curious mind who is passionate about furthering knowledge and health through scientific research. You must be highly motivated and detail-oriented.

The successful candidate should:

• hold a PhD in molecular or cellular biology, biochemistry, bioengineering or a very closely-related discipline
• be structured and responsible
• have an inquisitive mentality
• enjoy working as part of a team
• be fluent in written and spoken English
• have expertise in standard techniques of molecular biology and cell biology

Expertise in one or more of the following areas would be advantageous:

• stem cell biology
• skeletal growth research
• working with extracellular vesicles/other nanoparticles in biological settings
• endosomal trafficking
• radiation oncology

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Biomedicum A4, Solna campus.

https://ki.se/en/people/phillip-newton

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)
• A personal letter outlining your reasons for applying

Welcome to apply at the latest May 21, 2024

The application is to be submitted through the Varbi recruitment system.