Postdoctoral Researcher in Environmental Medicine

The mission at the Unit of Systems Toxicology is to perform top quality research to understand how different environmental exposures affect human wellbeing, focusing on the impact of chemicals and microbes on epithelial barrier function and immunity, and on development. We work with experimental and bioinformatics models and methods, including cells, tissues, zebrafish, and different omics analysis. We are now recruiting a Postdoctoral Researcher who will work with Associate Professor Emma Wincent on zebrafish-based research related to the impact of chemicals on tissue repair and metabolic function, as part of projects funded by the Swedish research council FORMAS and EU-HORIZON.

The project is centered upon identifying the impact of different chemicals, both naturally formed and man-made on tissue repair, stem cell differentiation, inflammatory signaling, metabolic function and growth/development. This will be performed using a range of zebrafish models and methods, working with embryonic life stages up to adulthood. The expected starting date is June 2024, and the position is temporary for 3 years.

We are looking for an ambitious, highly motivated and independent individual. Requirements for the position include a doctoral degree in areas related to tissue damage signaling and repair, and immunity. Hands-on advanced experience of working with zebrafish at different life stages, including embryonic, larval and adult, as experimental models, is required, as well as experience in generating novel zebrafish strains using different techniques including the Tol2-mediated and GAL4-UAS systems for transgenesis.  In addition to working with zebrafish, hands-on experience working with bioinformatics analysis, especially RNAseq and metabolomics, is required, and experience in integration of multiple OMICS layers is considered advantageous, as well as hands-on experience working with rodent animal models. Additional methods for which experience is required include morphological assessment of zebrafish, microscopy (brightfield and fluorescence), FACS, and gene expression analysis.

The candidate must be able to work within a team of scientists from different disciplines and nationalities, and fluency in English, both written and oral, is a requirement. The position also entails teaching and student supervision. Documented experience in supervision of master student or doctoral students is therefore a requirement.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

Institute of Environmental Medicine: https://ki.se/en/imm/institute-of-environmental-medicine 

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.