Description of workplace
This post-doctoral position 3D imaging of pulmonary vascular remodeling is part of the EU cofund research project AMBER, Advanced Multiscale Biological imaging using European Research infrastructures, will address scientific and sectoral gaps in biological imaging ranging from molecular, through cellular, to tissue, organ and organism levels of organisation, and is coordinated by LINXS Institute of advanced Neutron and X-ray Science. AMBER is funded by the EU Marie Skłodowska-Curie (MSCA) COFUND scheme. Around 14 postdocs will be recruited in the first call, with each fellowship lasting 36 months. AMBER has six core partners: Lund University/MAX IV, Sweden, the European Spallation Source (ESS), Sweden, the European Molecular Biology Laboratory (EMBL), Institut Laue-Langevin (ILL), France, the International Institute of Molecular Mechanisms and Machines, (IMOL), Poland, and the Leicester Institute of Structural and Chemical Biology, United Kingdom. The research group consists of the Karin Tran-Lundmark, who is a clinician scientist, two research nurses, a radiation physicist and three part time PhD students who are all medical doctors. For more information about the total announced post-doctoral positions within in the AMBER co-fund project please visit Here
Work duties and areas of responsibility
Your work will include clinical and biomedical projects. It will also include technique development work aimed at combining imaging techniques and data analysis to provide a more integrated picture of life processes in the context of health and disease. To be a postdoc fellow at the AMBER programme you will get unprecedented medical, biological, and methodological capabilities, with a profound potential impact for Europe’s next generation of research and researchers. When you have completed the AMBER programme you will be extraordinarily well equipped to further your career in academia, at infrastructures, in the health and MedTech sectors, and beyond.
This 3-year full time post doc project will focus on pulmonary vascular remodeling and underlying mechanisms in different types of pulmonary hypertension.Synchrotron-based phase contrast micro-CT will be combined with other methods like in situ hybridization and immunohistochemistry. Tissue from human patients as well as from animal models will be used. Software like Fiji and Amira will be used for visualization. The main focus will initially be pulmonary vascular remodeling in fibrosis, ie group 3 pulmonary hypertension. You will also be a mentor for the research nurses and PhD students for other ongoing projects in the lab. Participation during beamtimes at synchrotrons in different countries in Europe is expected (including shifts during the night), as well as active involvement in international collaborations.
Qualifications
Requirements for employment are:
- Candidate needs to have a maximum 8 years after a doctoral degree (PhD), as required by the Commission, in accordance with the Horizon-Europe MSCA cofund project Grant Agreement
- At least one original publication in a peer-reviewed journal
- A background in the relevant methods
- A complete application package submitted through the AMBER portal (including CV and detailed research plan), and finally
- Strict compliance with the MSCA mobility rule that the researcher must not have resided or carried out his/her main activity (work, studies, etc.) in the host organisation's country for more than twelve months in the three years immediately prior to the call deadline
- PhD within the medical field
- Previous experience with pulmonary research
- Excellent knowledge of biochemistry and molecular biology
- Hands-on skills (sectioning, in situ hybridization, immunohistochemistry, qPCR etc)
Additional qualifications for the position are:
- Previous hands-on experience from experiments at synchrotrons
- Good communication skills and Collaborative skills
- Good computer skills
- Teaching experience and Experience from supervising students in the laboratory
How to apply
For more information please visit Here
If you are interested in applying for more than one position (maximum 3) you must be prepared to make a full application for each individual position.
Applications shall be written in English and compiled into a PDF-file containing:
i) A Curriculum Vitae (europass format). This is created by registering and using the Europass portal here: https://europa.eu/europass/en/create-europass-cv. Your CV can then be exported to a PDF file that you use in your application. ii) A detailed research plan including any foreseen secondments (candidates can suggest more than the mandated one, they can also suggest their own secondments), schools and conferences as well as a templated budget plan. (as concise as possible, recommended about 3-5 pages, but at an absolute maximum 10 pages. The research plan should include a half page of summary/abstract. The template can be downloaded from the “For applicants” page, here: https://www.ambercofund.eu/for-applicants.
Additional texts to include in the PDF are:
iii) Letter of Commitment from any additional secondment partners the candidate wishes to bring
onboard.
iv) Evidence of English proficiency (minimum CEFR B22, also checked at interview). v) A draft Individual Career Development Plan (ICDP). vi) Two reference letters.
vii) Any additional documents to support the application.
viii) Ethical questionnaire (HE ethics checklist + research ethics commitment) link will be provided at the “For applicants” page, here: https://www.ambercofund.eu/for-applicants.
In addition, the application will require:
ix) Any candidate can apply for maximum of 3 positions. You must apply for each individual position. A list with order of preference of positions should be sent to the AMBER management. [email protected] The template can be downloaded from the “For applicants” page, here: https://www.ambercofund.eu/for-applicants. x) A pre-recorded video presentation (questionnaire-guided, via online video tool,
about 10min). Upon successful completion of the rest of the application procedure eligible candidates will be sent a link.
The interviews will start in April. For more information about AMBER, application and evaluation process etc please visit link
About the employment
The employment is time-limited to a minimum of two years, a maximum of three years according to the collective agreement on limited-time employment as a postdoctoral fellow (according to Collective Agreement). An appointment as a postdoctoral fellow is intended as an initial step in the career and as an opportunity to further deepen and broaden research competence.
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