Research Technician position

The Institute

The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies. 

In April 2021, the Centre for Genomic Regulation (CRG) received the renewal of the 'HR Excellence in Research ' Award from the European Commission. This is a recognition of the Institute's commitment to developing an HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and theCode of Conduct for the Recruitment of Researchers (Charter and Code). 

Please, check out our Recruitment Policy

The role  

Chromatin regulation has been related to a number of organism and cellular mechanisms, such as development and differentiation. The deregulation of chromatin profiles has been associated, thus, to the development and progression of multiple diseases, such as cancer, immune, metabolic and degenerative diseases. In this context, the identification of chromatin profiles and the comparison between different conditions is essential to understand the role of epigenetics in the development of such diseases as well as to follow-up possible treatments. FLEA-ChIP is a novel technology developed in the lab able to profile chromatin features from ultra-low input samples, such as liquid biopsies and rare or scarce samples. In collaboration with Oryzon Genomics, and with the goal of understanding the role of chromatin modifiers and histone modifications in the progression of rare diseases, the selected candidate will work in the experimental and computational analysis of clinical samples from healthy and diseased donors by FLEA-ChIP. The candidate will also participate in the implementation of the FLEA-ChIP in other contexts and in the further development of the technology.  

About the team

The overarching theme of the research in our lab is the understanding of the information encoded in genomic sequences, and how this information is processed in the pathway leading from DNA to protein sequences. More specifically, we are interested in the epigenetic regulation of gene expression and RNA processing, the relationship between molecular phenotypes and higher order endophenotypes and organismal phenotypes, and the identification of functional regions on the genome of all living beings. We are also committed to the development of experimental and computational tools to perform Genomics studies. 

Whom would we like to hire?  

Professional experience

Must Have

• You have a master's degree in biomedical sciences and five years of experience in/with experimental laboratories 

• You have proven experience in/ with molecular biology approaches and next generation sequencing 

• You have proven experience in computational data analysis of omics data 

Nice to have 

• PhD in biomedical sciences 

• Experience in single cell experimental and computational methods 

• Experience in epigenetics and epigenetic studies tools and analyse 

Education and training

• Master Degree in biomedical sciences required. 

• Candidates must have an excellent academic record, previous research experience and a strong commitment for scientific research 

Languages

• You are proficient in English 

Technical skills 

• You have advanced MS Office skills 

• You have skills on Molecular Biology procedures (quantitative PCR, cell culture, NGS library preparation, etc.) 

• You have skills on experimental methods development and improvement 

Competences  

• Highly developed organisational skills

• Ability to interact with others, both with colleagues within the group and from other groups inside and outside the CRG

• Good (academic) writing and presentation skills 

• Imagination, Motivation, Curiosity, Pro-activity, Critical thinking

The Offer – Working Conditions 

• Contract duration:Linked to the project, estimated 2 years.

• Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales 

• Target start date:April 1st 2024 

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section .

We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion,sexual orientation or gender identity.

The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.

Application Procedure

All applications must include:

All applications must be addressed to Dr. Sílvia Pérez-Lluch and be submitted online through the "Apply" button below.

Selection Process

• Pre-selection: The pre-selection process will be based on qualifications and expertise reflected on the candidates CVS. It will be merit-based. 

• Interview: Preselected candidates will be interviewed by the Hiring Manager of the position and a selection panel if required. 

• Offer Letter: Once the successful candidate is identified the People department will send a Job Offer, specifying the start day, salary, working conditions, among other important details.  

Deadline: Please submit your application by 29/03/2024. 

The contract will be financed by Ministerio de Ciencia e Innovación. Ref project: CPP2022-009549.