Mechanobiology of cancer progression, Platform validation with anticancer agents, 2024_ASSEGNI_DCMC_42

24 May 2024
Job Information

Organisation/Company

Politecnico di Milano

Research Field

Engineering

Researcher Profile

Recognised Researcher (R2)
Leading Researcher (R4)
First Stage Researcher (R1)
Established Researcher (R3)

Country

Italy

Application Deadline

15 Jun 2024 - 23:59 (UTC)

Type of Contract

To be defined

Job Status

Not Applicable

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The project is focused on the use of human breast cancer cells adhering to 3D polymeric microscaffolds to model microtumours. The microtumours will be implanted in vivo in the respiratory membrane of embryonated avian eggs, in order to elicit a fibrotic foreign body reaction in the microtumours. The geometry of the 3D microscaffolds will be varied to condition the infiltration of the microtumours by the vessels and cells of the embryo, recreating an array of tumour microenvironments at various stages of fibrotic progression. We will predict mass transport of anticancer drugs by multiphysics modelling. This study model will be validated with approved and investigational anticancer drugs whose clinical outcome is known to depend on the level of tumour fibrosis.

Requirements
Additional Information
Eligibility criteria

Relevance of qualifications with the research programme object of selection

Consistency of the candidate's overall profile with respect to the content of the research programme for selection

Close relevance of publications submitted with the research programme object of selection

Interview aimed at ascertaining the candidate's aptitude for the research object of the selection

Eligible destination country/ies for fellows:

• EUROPE

Eligibility of fellows: country/ies of residence:

• All

Eligibility of fellows: nationality/ies:

• All

Selection process

In order to participate in the selection, please read the call ("bando") available at the following website: https://www.polimi.it/en/faculty/working-at-the-politecnico/research-gr…

Website for additional job details

https://www.polimi.it/docenti-e-staff/bandi-e-concorsi/bandi-per-assegni-di-ric…

Work Location(s)

Number of offers available

1

Company/Institute

Politecnico di Milano

Country

Italy

Geofield

Where to apply

Website

https://aunicalogin.polimi.it/aunicalogin/getservizio.xml?id_servizio=1079

Contact

City

Milan

Website

https://www.polimi.it/

STATUS: EXPIRED