Postdoc – Molecular and bioinformatic-based identification of optimized enzymes for biotechnological applications

Updated: 30 days ago
Location: Lich, HESSEN
Deadline: 20 Apr 2024

27 Mar 2024
Job Information
Organisation/Company

Forschungszentrum Jülich
Research Field

All
Researcher Profile

Recognised Researcher (R2)
Established Researcher (R3)
Country

Germany
Application Deadline

20 Apr 2024 - 22:00 (UTC)
Type of Contract

To be defined
Job Status

Other
Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Work group:

IBG-4 - Bioinformatik

Area of research:

Scientific / postdoctoral posts

Job description:

Your Job:

  • Analyzing RNAseq data with respect to the identification and functional annotation of genes involved in, for example, cell wall degradation, carbon flux etc.
  • Screening metagenomic and genomic data using deep learning methods in order to identify degrading enzymes from different data resources
  • Using Hidden Markov Models and similar tools as well as machine learning for the identification of novel and better enzyme variants from a large proteome compendium
  • Generating structural models of enzymes and using machine learning methods to predict their enzymatic function and characterize their molecular recognition properties
  • Using machine learning methods and simulation techniques to understand environmental effects on the enzymes and improving their stability and activity
  • Publishing the scientific results in international journals and traveling to national and international conferences
  • (Co)-supervising PhD students

Your Profile:

  • University degree (Master) and doctorate in bioinformatics, computer science, data science, biophysics, or life science-related fields with a proven track record in bioinformatics, biophysics, data analysis, and simulation sciences
  • Very good practical experience in molecular biology, Next Generation Sequencing, and structural biology
  • Extensive experience in analyzing large datasets (especially genomics, transcriptomics, metagenomics, enzyme data, and structural data)
  • Experience with the application of machine learning methods for data analysis and interpretation
  • Knowledge in programming languages (e.g. Java, Rust, C/C++, Python) and statistical analysis using R/BioConductor/python
  • Proven scientific communication skills in the form of scientific publications or equivalent
  • Willingness to complement and collaborate with existing research units at the research center
  • Excellent English language skills, both written and spoken are a requirement due to the international nature of the institute and collaborations

Our Offer:

We work on the very latest issues that impact our society and are offering you the chance to actively help in shaping the change! We support you in your work with:

  • A large research campus with green spaces, offering the best possible means for networking with colleagues and pursuing sports alongside work
  • Outstanding scientific and technical infrastructure
  • Creative and international team that conducts research at the frontiers of science
  • The Forschungszentrum Jülich is one of the largest research centres in Europe with excellent scientific equipment, including the fastest supercomputer in Europe, is located on a green campus, and near the cultural centres of Cologne, Düsseldorf and Bonn
  • A highly motivated group and an international and interdisciplinary working environment in one of the largest research institutions in Europe
  • The possibility to develop your own research program in line with the institute and center strategy
  • Flexible working hours in a full-time position with the option of slightly reduced working hours
  • 30 days of annual leave and provision for days off between public holidays and weekends (e.g. between Christmas and New Year)
  • Targeted services for international employees, e.g. through our International Advisory Service

We offer you an exciting and varied role in an international and interdisciplinary working environment. The position is for a fixed term of 2,5 years, with possible long-term prospects. Salary and social benefits will conform to the provisions of the Collective Agreement for the Public Service (TVöD-Bund), pay group EG 13, depending on the applicant’s qualifications and the precise nature of the tasks assigned to them.

In addition to exciting tasks and a collaborative working atmosphere at Jülich, we have a lot more to offer: go.fzj.de/benefits

We welcome applications from people with diverse backgrounds, e.g. in terms of age, gender, disability, sexual orientation / identity, and social, ethnic and religious origin. A diverse and inclusive working environment with equal opportunities in which everyone can realize their potential is important to us.

This research center is part of the Helmholtz Association of German Research Centers. With more than 42,000 employees and an annual budget of over € 5 billion, the Helmholtz Association is Germany's largest scientific organisation.


Requirements
Additional Information
Website for additional job details

https://www.fz-juelich.de/en/careers/jobs/2024-114

Work Location(s)
Number of offers available
1
Company/Institute
Forschungszentrum Jülich
Country
Germany
City
Jülich
Geofield


Where to apply
E-mail

[email protected]
Website

https://www.fz-juelich.de/en/careers/jobs/2024-114

Contact
City

Jülich
Website

https://www.fz-juelich.de/portal/home
Street

Wilhelm-Johnen-Straße
Postal Code

52428
E-Mail

[email protected]
Phone

+49 2461 61-0
Fax

+49 2461 61-8100

STATUS: EXPIRED