Understanding the role of RNA methylation in Sjogren disease

8 Apr 2024
Job Information

Organisation/Company

Université Paris-Saclay

Research Field

Medical sciences » Other
Biological sciences » Other

Researcher Profile

First Stage Researcher (R1)

Country

France

Application Deadline

1 Jun 2024 - 01:00 (Europe/Paris)

Type of Contract

Temporary

Job Status

Full-time

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The Autoimmunity Research Team is seeking passionate and self-motivated post-doctoral candidates to embark on research endeavors focusing on the role of RNA methylation in mice models of Sjogren disease (SjD). The position is currently available and funded for 2 years, subject to renewal.

Sjögren disease (SjD) is a prototypic systemic autoimmune disease affecting 0.1% of the population and characterized by the dysfunction of salivary and lacrimal glands, along with numerous systemic complications and an increased risk of lymphoma. For a long time orphaned by treatment, there is now a revolution under way, with several phase II and phase III trials in the field.

Environment: Our team, led by Pr Xavier Mariette - within Inserm UMR 1184, CEA, Université Paris-Saclay, is dedicated to exploring the pathophysiology, epidemiology, and treatment strategies for various autoimmune conditions. Our research encompasses rheumatoid arthritis, SjD and lymphomas associated with autoimmune diseases, among other autoimmune-related disorders. We are committed to advancing our understanding of these complex diseases, investigating the underlying mechanisms driving their progression, and identifying novel therapeutic interventions. Through multidisciplinary approaches and collaborative efforts, we aim to make significant strides in improving patient outcomes and quality of life for individuals affected by autoimmune disorders. The laboratory provides state-of-the-art facilities for cellular and molecular biology, and top-level rheumatology/immunology research and an animal facility. The host lab has a particular interest in translating its basic science discoveries into translational research.

Candidates: The applicants are expected to have a strong background in immunology and immunopathology (PhD), RNA biology and cellular biology as well as in mice work, including injections and organ recuperation. The ideal candidates should be highly motivated, curious, and enthusiastic to work in a highly collaborating team. Proven ability to identify research objectives and meet agreed deadlines, self-motivation, flexibility, and assistance to other ongoing research work is essential. Excellent written and communication skills in English are required. Bioinformatics and international training will constitute an advantage.

Application: Candidates are invited to contact Dr. Rami Bechara ([email protected] ) for further details.

Please send an application with the following:

- Cover letter

- Concise summary of previous research activities

- Curriculum vitae including publication list and contact details for 2-3 referees

Requirements

Research Field

Biological sciences » Other

Education Level

PhD or equivalent

Skills/Qualifications

The applicants are expected to have a strong background in immunology and immunopathology (PhD), RNA biology and cellular biology as well as in mice work, including injections and organ recuperation. The ideal candidates should be highly motivated, curious, and enthusiastic to work in a highly collaborating team. Proven ability to identify research objectives and meet agreed deadlines, self-motivation, flexibility, and assistance to other ongoing research work is essential. Excellent written and communication skills in English are required. Bioinformatics and international training will constitute an advantage.

Languages

ENGLISH

Level

Excellent

Research Field

Biological sciences » Other

Years of Research Experience

1 - 4

Additional Information
Work Location(s)

Number of offers available

1

Company/Institute

Inserm UMR 1184

Country

France

Geofield

Where to apply

E-mail

[email protected]

Contact

Website

https://www.universite-paris-saclay.fr/group/1/nodes

STATUS: EXPIRED