26 Mar 2024
Job Information
- Organisation/Company
Muséum National d'histoirte Naturelle- Research Field
Chemistry » Biochemistry- Researcher Profile
Recognised Researcher (R2)
Leading Researcher (R4)
First Stage Researcher (R1)
Established Researcher (R3)- Country
France- Application Deadline
30 Apr 2024 - 22:00 (UTC)- Type of Contract
Temporary- Job Status
Full-time- Offer Starting Date
1 Jun 2024- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
He/she will lead the extraction, purification and structural analysis of the different compounds
of interest. The candidate will use the latest chemoinformatics tools in order to annotate
the metabolomes of the preselected strains (MetWork, DEREPLICATOR, SIRIUS) to
thus help with the purification of compounds which will essentially be based on
separation techniques, with monitoring by LC-MS. The structural analysis will be
carried out by high resolution mass spectrometry and NMR (600 MHz cryoprobe).
Absolute configurations of asymmetric centers will be also examined if necessary.
Finally, the obtained structures will be compared with the putatively corresponding
biosynthesis gene cluster in order to propose a description of their specific biosynthesis
pathway.
Requirements
Specific Requirements
Desired experience: strong skills in analytical chemistry, separation techniques,
structural analysis, chemoinformatics approaches for metabolome annotation.
Desired level of study: doctorate/engineer in chemistry of natural substances or analytical
chemistry
Additional Information
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Muséum National d'histoirte Naturelle
- Country
- France
- City
- Paris
- Geofield
Where to apply
- Website
https://www.abg.asso.fr/fr/candidatOffres/show/id_offre/121739
Contact
- Website
https://mcam.mnhn.fr/fr
STATUS: EXPIRED
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