Post doc researcher in autophagy, cell biology and neuronal physiology and pathophysiology

7 Feb 2024
Job Information

Organisation/Company

Universite de Montpellier

Department

Human Resources

Research Field

Biological sciences » Biology

Researcher Profile

First Stage Researcher (R1)

Country

France

Application Deadline

6 Mar 2024 - 23:59 (Europe/Paris)

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

38

Offer Starting Date

1 Apr 2024

Is the job funded through the EU Research Framework Programme?

HE

Reference Number

2024-R0018

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description
Project title: Cooperative regulation of neuronal autophagy by the Sigma-1 receptor and Wolframine responsible for Wolfram syndrome Project acronym: SIRWOLFPHAGY Overall duration of the project: 3 years Summary description of the project: The aim of the project is to study the role of selective autophagy in neuronal physiology and pathophysiology (Wolfram syndrome, Alzheimer's disease). Our laboratory is currently interested in the mechanisms by which selective neuronal autophagy is regulated by the wolframin-sigma-1 receptor-NCS1 complex. Main mission : To carry out this project, biochemical, cellular and microfluidic approaches will be implemented in the laboratory by the candidate as well as in vivo animal models (mouse and zebrafish) and human tissue samples (patient fibroblasts) in collaboration with Guy de Chauliac hospital. Definition of the tasks to be accomplished: The candidate will perform cell biology experiments (primary neuron culture, NSC34 cell culture, western blot, microfluidic experiments, elisa) to study how the S1R-WFS1-NCS1 complex modulates autophagy. Precise description of the event or objective result determining the end of the contractual relationship as well as the methods for evaluating and controlling this result: Final report sent to the National Research Agency. Job constraints: Work on weekends.
Requirements

Research Field

Biological sciences » Biology

Education Level

PhD or equivalent

Skills/Qualifications
Applicants with a PhD in molecular and cellular biology obtained within the past year and with experience in the areas of autophagy, cell signaling, neuronal culture and microfluidic chambers are encouraged to apply.
Additional Information
Selection process

Please send your CV and cover letter by email before 03/06/2024.

Work Location(s)

Number of offers available

1

Company/Institute

University of Montpellier

Country

France

Geofield

Where to apply

E-mail

[email protected]

Contact

City

Montpellier

Website

http://www.umontpellier.fr/

Street

163 rue Auguste Broussonnet

Postal Code

34000

STATUS: EXPIRED