Iron oxide magnetic nanoflowers as potential theranostics: Assessing the relationship between their structure-properties and their function in vivo
19 Mar 2024
Job Information
- Organisation/Company
Sorbonne University- Department
Chemistry Department- Research Field
Biological sciences » Laboratory animal science
Medical sciences » Cancer research
Chemistry » Biochemistry- Researcher Profile
First Stage Researcher (R1)- Country
France- Application Deadline
7 Apr 2024 - 12:00 (Europe/Paris)- Type of Contract
Temporary- Job Status
Full-time- Hours Per Week
35- Offer Starting Date
1 Jun 2024- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
The field of nanomedicine is receiving increasing attention and has enormous potential for a plethora of pathological conditions, including cancer. One of the main advantages of nanomaterials is the ability to combine multiple modalities in one platform, allowing the nanomaterials to be used simultaneously for diagnostic and therapeutic applications and to use multiple therapeutic options simultaneously. Among these nanoparticles are iron oxide magnetic nanoflowers whose structure-property-function relationship is investigated in PHENIX lab showing exciting functions in heat generation (magnetic hyperthermia, photothermia) as well as in MRI and MPI imaging. However, the main bottlenecks hindering the full use of nanomaterials for biomedical purposes is the need for a higher level of selectivity in terms of targeted delivery of the nanomaterials to the target cells, along with the development of new, alternative therapeutic options. In this postdoc and in the frame of a collaboration between Inorganic Colloids group in PHENIX (Sorbonne University, France) and NanoHealth and Optical Imaging Group (KU Leuven, Belgium) we propose to investigate these topics which are central in a multidisciplinary way by making extensive use of non-invasive imaging (optical imaging and magnetic particle imaging) to investigate the biodistribution and functionality of the nanoformulations.
Requirements
- Research Field
- Biological sciences » Laboratory animal science
- Education Level
- PhD or equivalent
- Research Field
- Medical sciences » Cancer research
- Education Level
- PhD or equivalent
- Research Field
- Chemistry » Biochemistry
- Education Level
- PhD or equivalent
Skills/Qualifications
Candidate profile: The applicant holds a PhD in the fields of biology, medical sciences, pharmaceutical sciences, biochemistry, bioengineering, or similar and has: i) Experience in handling and testing mice and performing related biochemical tests, ii) Experience working with in vivo optical imaging. iii) Experience with histology and all related skills, iii) Experience with fluorescence microscopy is desirable but not a must, iii) Experience with MPI is desirable but not a must, iv) Ideally, the applicant has a Felasa B animal handling certificate. Applicant must be able to communicate well in English.
Main responsibilities: i) Applicant must have sound knowledge and experience in performing cell culture techniques and basic in vitro assays, ii) Must be able to perform non-invasive imaging tasks, example; optical imaging, FLECT-CT and MPI. The latter two are desirable but not a must, iii) The applicant will work with different mouse tumor models. This work includes intravenous and subcutaneous injections, dissection of the mice, and processing of different organs.
- Languages
- ENGLISH
- Level
- Excellent
- Research Field
- Biological sciences » Laboratory animal scienceMedical sciences » Cancer researchChemistry » Biochemistry
- Years of Research Experience
- 1 - 4
Additional Information
Benefits
Monthly salary is 2 889,51 € (monthly gross)
Selection process
Interested and highly motivated candidates should apply by submitting to
: [email protected] r ; [email protected]
a cover letter stating why they are interested in this position, a full CV with a list of publications, and two academic references (with address, phone number and email).
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- NanoHealth and Optical Imaging Group at KU Leuven in Belgium
- Country
- Belgium
- City
- Leuven
- Geofield
Where to apply
[email protected]
Contact
- City
PARIS- Website
https://phenix.cnrs.fr/- Street
case 51 4 place Jussieu 75005 PARIS- Postal Code
75005
[email protected]
[email protected]
STATUS: EXPIRED
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