Proteomics Core Facility Manager - DTU Bioengineering

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Proteomics Core Facility Manager - DTU Bioengineering
Kgs. Lyngby, Denmark

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Job Description

The Proteomics Core Facility at the Department of Biotechnology and Biomedicine (DTU Proteomics Core) has an opening for a position as operational manager. The position will be available from April 2024 or as soon as possible.

The DTU Proteomics Core is a very well-equipped academic proteomics core facility and supports academic and industrial scientists both at DTU and beyond by providing a wide range of proteomics services using various platforms for protein and peptide separation, state-of-the-art mass spectrometers for LC-MS analysis and specialized bioinformatics tools for data analysis. The facility provides service and engages in collaborations within advanced labeled and label-free quantitative proteomics, targeted proteomics and Data-Independent Acquisition workflows. We have a long-standing record and focus on high-sensitivity analysis of very limited sample amounts, all the way down to single cells. 

The DTU Proteomics Core is located at the DTU Lyngby campus in a recently constructed building housing ultra-modern, purpose-built laboratories for protein research. Currently, the facility hosts five ThermoFisher Orbitrap mass-spectrometers (two Eclipse Tribrids, one Exploris480 and two Q Exactive Classics), with FAIMSPro capability on the latest-generation instruments. For advanced chromatography methods, we have a U-3000 offline high pH fractionation system, and utilize online U-3000, Easy nLC1200 and EvoSep One platforms to support all modern proteomics approaches.

Responsibilities and tasks
The position implies daily supervision of all aspects of the core facility in close collaboration with the lab manager. The core manager is responsible for managing staff, maintaining equipment, developing and following standard operating procedures, developing and maintaining customer connections and running the projects. Budgeting and invoicing will be conducted together with the lab manager.

The future of the DTU Proteomics Core will be significantly influenced by the professional contribution of the applicant. You will be involved in important biotechnological, biomedical and chemical related projects. This includes high-profile collaborations with leading manufacturers in mass spectrometry instrument technology, chromatography and sample preparation. You will also contribute to training activities, including introductions of technical relevant information to the customers, as well as supervision of visiting students and postdocs. Own research in technological developments in proteomics will be strongly encouraged. Applying for own research grants is not obligatory but highly recommended.

Qualifications
Candidates should have a PhD or equivalent, with documented experience in day-to-day handling of modern mass spectrometry instrumentation of at least 5-6 years.

The ideal candidate has a strong background in mass spectrometry and proteomics, as well as excellent understanding of the technology involved, including liquid chromatography, high-resolution mass spectrometry, bioinformatics and related software. A strong grasp on approaches such as DDA, DIA, and PRM is essential, including downstream analysis using e.g. Proteome Discoverer, Spectronaut, Spectromine, MaxQuant or Skyline.

The applicant should possess a core understanding of biochemistry, molecular biology, and biotechnology and be familiar with typical proteomics tasks.

Organizational, managerial, leadership and interpersonal skills are of particular importance. The candidate should preferably have experience with managing a MS facility and have knowledge of the practical, legal and financial aspects. The ideal applicant must have strong motivation and excellent work ethics. The ability to effectively interact with the research and technical staff within the group as well as external researchers in a team-oriented manner is a must.

Proficiency in English is essential, as this is the working language.

We offer
We offer an interesting and challenging job in an international atmosphere with the focus on research, teaching, innovation and scientific advice for the benefit of the surrounding community. We place emphasis on a high level of professionalism among our staff, so skills development is an integral part of our organization. We offer a great flexibility in the position. In the area of technical and natural sciences, DTU is one of the leading research and education institutions in Europe.

Salary and terms of employment
The appointment will be based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed with the relevant union.

The position is permanent.

Application and contact
Please submit your online application no later than 22 February 2024. Open the “Apply now” link, fill out the form and attach your:

• Application (cover letter)
• CV
• Diploma (MSc/PhD)
• List of publications

Further information may be obtained from Professor Susanne Brix Pedersen, [email protected]  

You can read more about DTU Bioengineering at www.bioengineering.dtu.dk  

Applications and enclosures received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

The Department of Biotechnology and Biomedicine (DTU Bioengineering) is an international leader in the areas of biotechnology and biomedicine. Our engineering approach to all aspects of biotechnology and biomedicine positions us as a valuable player with unique competences in a growing bio-based economy and with health systems transforming towards personalized medicine. We have a clear focus on the needs in the life science- and biotech industries and point towards innovation, new businesses, and scientific services for the benefit of society. The department has extensive collaborations with national and international research units and industry. DTU Bioengineering has approx. 400 employees, of which 2/3 are scientific staff. The department is located at DTU Lyngby Campus.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

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Job Info

• Job Identification 3139
• Job Category TAP
• Posting Date 02/08/2024, 04:18 AM
• Apply Before 02/22/2024, 05:59 PM
• Locations Søltofts Plads, Kgs. Lyngby, 2800, DK

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