Management of intracellular protein aggregates in stressed bacteria

(ref. BAP-2022-521)

Laatst aangepast : 17/07/2022

The Department of Microbial and Molecular Systems (M²S) of the KU Leuven is looking for a motivated pre-doctoral or postdoctoral researcher to take part in a research program concerning the impact of protein aggregates on bacterial physiology.

Project

Given the fundamental importance of protein quality control in cellular physiology and of proteotoxic stresses in the battle against bacterial pathogens, there is an urgent need for a more in depth understanding of the management and impact of intracellular protein aggregates (PAs). Using the Escherichia coli bacterium as a highly tractable and relevant model system for both an elementary (prokaryotic) cell and a bacterial pathogen, this project will combine advanced genetics and live cell biology approaches to address the molecular causes and phenotypical consequences of intracellular protein aggregation.

Profile

The applicant should either hold a PhD degree, or a degree that formally qualifies her/him to enter the PhD program of the Leuven Arenberg Doctoral School (http://set.kuleuven.be/phd/).An outspoken interest in microbiology, molecular biology, cell biology and analytical genetics, together with advanced command of both spoken and written English is mandatory.

Offer

A full time PhD or Postdoc position is offered. Detailed employment conditions will be shared upon contact.

Interested?

Applicants should upload a detailed Curriculum Vitae together with a concise letter of motivation in the online portal.

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