Downstream Bioprocess Engineer

1 May 2024
Job Information

Organisation/Company

KU Leuven

Research Field

Engineering » Biomedical engineering

Researcher Profile

Recognised Researcher (R2)

Country

Belgium

Application Deadline

1 Jul 2024 - 00:00 (UTC)

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

38 hours/week

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Reference Number

BAP-2024-257

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

WHAT WILL YOU DO?As an expert in downstream purification for AAV vectors, you will• optimize the DSP for AAV vectors including clarification, chromatography purification and formulation using existing and newly developed technologies as well as those developed in-house• design and implement scale-up methodologies for AAV vector purification with quality, yield and cost-efficiency in mind• apply bioprocess engineering strategies to optimize the AAV purification methods towards GMP-compatible standards• investigate and develop novel technologies in the current manufacturing process • write and review technical documents including SOPs and reports of the DSP activities.
But of course, you’re also a team player.• You are responsible for AAV vector manufacture for internal projects as well as for collaborations with external partners in biotech and pharma.• You will work with the quality team responsible for AAV vector analytics.• Training and managing a small team of technicians is also part of your job.• And you will effectively communicate the info gathered from your data analysis and report back to the relevant team members and collaborators.

Requirements

Research Field

Engineering

Education Level

PhD or equivalent

Languages

ENGLISH

Level

Excellent

Additional Information
Benefits

WHAT DO WE OFFER?• An interesting job in a team of ± 20 people with different backgrounds and expertise, all sharing the same ambition: delivering new therapeutics to patients.• The opportunity to work in a well-funded, state-of-the-art lab that nurtures novel research initiatives.• Gaining deep knowledge of gene therapy research and the associated development process.• Superb career development opportunities with a long-term perspective.• The chance to connect to a dynamic network of both academies and industrial partners in an international setting. 

Eligibility criteria

WHAT DO WE EXPECT?You’re our ideal DSP engineer if you have:• a PhD in Biochemistry, Bio-engineering, Biomedical Sciences or equivalent through relevant experience• expertise in DSP development for biologics• hands-on experience with filtration and chromatography instruments such as AKTA Flux, AKTA Purifier/Pure/Explorer/Avant• strong knowledge on membrane filtration (normal flow and tangential flow) and chromatography (affinity, ion exchange, size exclusion)• a self-starting, pro-active attitude, being able to identify and tackle DSP challenges with minimal guidance• the ability to take initiative, work independently, and drive projects forward with minimal supervisionIf you have experience in working with viral vectors, that’s a plus.
And we’d like you to• easily understand (statistical) data analysis and quality management• work detail-oriented• strive for continuous improvement of yourself and your work• have excellent communication skills• can work effectively within a team• know how to prioritize and navigate your work in a fast-paced and rapidly evolving research environment• speak and write English fluently

Selection process

For more information please contact Prof. dr. Els Henckaerts, tel.: +32 16 37 61 96, mail: [email protected] or Mrs. Irina Thiry, tel.: +32 16 37 40 42, mail: [email protected] .
You can apply for this job no later than 01/07/2024 via the online application tool

Work Location(s)

Number of offers available

1

Company/Institute

KU Leuven

Country

Belgium

State/Province

Vlaams Brabant

City

Leuven

Postal Code

3000

Street

Leuven

Geofield

Where to apply

Website

https://easyapply.jobs/r/IkdVtLI21PoLtI29yD5Q

Contact

State/Province

Leuven

City

Vlaams Brabant

Street

Leuven

Postal Code

3000

E-Mail

[email protected]

STATUS: EXPIRED