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compounds. The post holder will be responsible for carrying out own academic research and will be actively involved in planning and leading the development of AI for RNA-drug interactions. You will be
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Newman at Centre for Medicines Discovery, Nuffield Department of Medicine. You will be responsible for expressing and purifying human helicase proteins for assay development and X-ray crystallography and
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. The CMD is made up of several teams; Structural and Functional Biology; Technologies; Drug Discovery; and Research Informatics. Together these units drive several major collaborative initiatives, involving
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substantial body of work already performed by this team, but the main objective is to enable these calculations to find use in the early hit-to-lead stages of drug-design. This is a full-time fixed-term post up
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implement the technological advances to realise the potential of mass photometry as a transformative biophysical tool for molecular biophysics, drug discovery and diagnostics. The project aims at both
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to undertake translation work at the interface between academic research and pharmaceutical target and drug discovery in an exceptional setting. This work will develop novel biomarkers to better understand
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translational work at the interface between academic research and pharmaceutical target and drug discovery in an exceptional setting. The project will examine metabolomic biomarkers of endolysosomal dysfunction
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spanning from pre-clinical discovery to Phase III clinical efficacy trials. As Senior Immunologist, you will take a leading role in the development and evaluation of novel experimental medicine and vaccine
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metabolic pathways to severe mental illness”. The project aims to find causal pathways by which immune and metabolic factors lead to severe mental illness, as a basis for new, personalised therapeutics
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experience working with mouse in vivo models, and knowledge in target discovery and drug development. Holding a Home Office personal license (PIL) for animal experimentation would also be advantageous