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University Utrecht and Chemical Biology and Drug Discovery- University Utrecht). Background: Effective treatment of bacterial infections is threatened by increasing rates of antibiotic resistance. Antibiotic
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Netherlands, a maternity allowance is standard for 16 weeks. Childcare is available at and near the Bio Science Park. Where will you be working You will be working in the division of Drug Discovery and Safety
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these research themes for highly informative drug discovery by nuclear magnetic resonance. We believe that, eventually, magnetic resonance can provide an in-depth biophysical characterisation of drug candidates in
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lab-on-chip systems. At the same time, you will be performing sophisticated biological assays, multi-omics approaches to validate and benchmark the models and find biomarkers. This position offers a
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integrated risk-model based on blood, tissue and imaging data. By extension, this project will help built a framework to determine the efficacy of (novel) drugs in individual lymphoma patients in a clinical
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then depends on local conditions, which vary, among others, due to changes in local drug concentrations caused by nearby bacteria that degrade or export the drug. Your task will be to construct strains
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drug concentrations caused by nearby bacteria that degrade or export the drug. Your task will be to construct strains of the bacterium Escherichia coli with common resistance mechanisms against
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the field of Computer-Aided Drug Design (CADD). This discipline plays an increasingly important role in the process of drug discovery and aims to reduce the costs in both time and resources in the drug
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). This discipline plays an increasingly important role in the process of drug discovery and aims to reduce the costs in both time and resources in the drug discovery process, also facilitating higher success rates in
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discovery and aims to reduce the costs in both time and resources in the drug discovery process, also facilitating higher success rates in subsequent clinical trials. Whether your expertise lies in structure